Now showing items 21-30 of 577
Diuron metabolites and urothelial cytotoxicity: In vivo, in vitro and molecular approaches
(Toxicology, 2013-12-15) [Artigo]
Diuron is carcinogenic to the rat urinary bladder at high dietary levels. The proposed mode of action (MOA) for diuron is urothelial cytotoxicity and necrosis followed by regenerative urothelial hyperplasia. Diuron-induced ...
Clinical presentation and salivary gland histopathology of paediatric primary Sjogren's syndrome
(Clinical and Experimental Rheumatology, 2011-05-01) [Artigo]
ObjectiveExplore the presentation, diagnostic criteria and exocrine gland histopathology of paediatric primary Sjogren's syndrome (PPSjS).MethodsA case series of 8 children is reported and American-European Consensus Group ...
Expression of 8-oxoguanine Glycosylase in Human Fetal Membranes
(American Journal of Reproductive Immunology, 2014-07-01) [Artigo]
Problem The most common DNA lesion generated by oxidative stress (OS) is 7, 8-dihydro-8-oxoguanine (8-oxoG) whose excision repair is performed by 8-oxoguanine glycosylase (OGG1). We investigated OGG1 expression changes in ...
The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation
(Virology, 2011-04-10) [Artigo]
KSHV LANA1, a latent protein expressed during chronic infection to maintain a viral genome, inhibits major histocompatibility complex class I (MHCI) peptide presentation in cis as a means of immune evasion. Through deletional ...
What is your diagnosis? Hepatosplenomegaly in a howler monkey (Alouatta fusca)
(Veterinary Clinical Pathology, 2012-09-01) [Artigo]
Dose-response of diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] in the urothelial mucosa of Wistar rats
(Toxicology, 2013-08-20) [Artigo]
Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a herbicide that induced urothelial tumors in the urinary bladder of Wistar rats fed 2500. ppm during a long-term study. The currently suggested non-genotoxic mode of ...
FOXE1: methylation and gene expression in canine osteosarcoma cell culture
(Online Journal of Veterinary Research, 2014) [Artigo]
Gene expression profiles in a canine osteosarcoma (OSA) cell culture could identify chemotherapeutic targets and sort useful from useless prognostic groups. This could allow for more personalized treatment of OSA based on ...
Dietary whey protein lessens several risk factors for metabolic diseases: a review
(Lipids in Health and Disease, 2012-06-07) [Artigo]
Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies ...
Cutaneous myxosarcoma in a Syrian hamster (Mesocricetus auratus)
(Semina: Ciências Agrárias, 2011-01-01) [Artigo]
The pathological findings in a 2-years-old Syrian hamster (Mesocricetus auratus) with a cutaneous myxosarcoma are described. Grossly, there was a large cutaneous mass in the right cervical region. Microscopical evaluation ...
Effectiveness of a 10-wk Lifestyle Modification Program in Reducing Hypertension in Brazilian Free-Living Adults
(Faseb Journal, 2017-04-01) [Resumo]