Now showing items 1-6 of 6
No relationship between subchronic fluoride intake and DNA damage in Wistar rats
(Caries Research, 2004-01-01) [Artigo]
Fluoride has been widely used in dentistry because it is an effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury on the genetic apparatus. ...
Does toxoplasmosis cause DNA damage? An evaluation in isogenic mice under normal diet or dietary restriction
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2004-04-11) [Artigo]
Toxoplasmosis is an anthropozoonotic widespread disease, caused by the coccidian protozoan parasite Toxoplasma gondii. Since there are no data regarding the genotoxicity of the parasite in vivo, this study was designed to ...
Absence of carcinogenic and anticarcinogenic effects of annatto in the rat liver medium-term assay
(Food and Chemical Toxicology, 2004-10-01) [Artigo]
Annatto (Bixa orellana L.) is a natural food colorant extensively used in many processed foods, especially dairy products. The lower cost of production and the low toxicity, make annatto a very attractive and convenient ...
Relationships between cagA, vacA, and iceA genotypes of Helicobacter pylori and DNA damage in the gastric mucosa
(Environmental and Molecular Mutagenesis, 2004-01-01) [Artigo]
Helicobacter pylori (H. pylori) is believed to dispose carriers to gastric cancer by inducing chronic inflammation. The inflammatory processes may result in the generation of reactive oxygen and nitrogen species that damage ...
Lack of genotoxicity of formocresol, paramonochlorophenol, and calcium hydroxide on mammalian cells by comet assay
(Journal of Endodontics, 2004-08-01) [Artigo]
Formocresol, paramonochlorophenol, and calcium hydroxide are widely used in dentistry because of their antibacterial activities in root canal disinfection. However, the results of genotoxicity studies using these materials ...
Fluoride does not induce DNA breakage in Chinese hamster ovary cells in vitro.
(Pesquisa Odontológica Brasileira = Brazilian Oral Research, 2004-07-01) [Artigo]
Fluoride has been widely used in dentistry because it is a specific and effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury to genetic material. ...