Now showing items 1-6 of 6
Improvement of the oral praziquantel anthelmintic effect by cyclodextrin complexation
(Journal of Drug Targeting, 2010-01-01) [Artigo]
Schistosomiasis is a parasitic disease which kills a half million people per year, a I I over the world. Praziquantel (PZQ) is the drug-of-choice for schistosomiasis because of its effectiveness, ease of administration, ...
Preparação e caracterização físico-química de complexos de inclusão entre anestésicos locais e hidroxipropil-beta-ciclodextrina
(Química Nova, 2007-08-01) [Artigo]
S(-) Bupivacaine (S(-)BVC) and Lidocaine (LDC) are widely used local anesthetics (LA). Hydroxypropyl beta-cyclodextrin (HP-beta-CD) is used as a drug-carrier system. The aim of this work was to characterize inclusion ...
Caracterização do complexo de inclusão ropivacaína: β-ciclodextrina
(Química Nova, 2007-10-01) [Artigo]
Characteriza of the inclusion complex ropivacaine: β-cyclodextrin. Ropivacaine (RVC) is a widely used local anesthetic. The complexation of RVC with β-cyclodextrin (β-CD) is of great interest for the development of more ...
Non-inclusion complexes between riboflavin and cyclodextrins
(Journal of Pharmacy and Pharmacology, 2012-06-01) [Artigo]
Objectives To investigate the molecular interaction between beta-cyclodextrin (beta CD) or hydroxypropyl-beta-cyclodextrin (HP beta CD) and riboflavin (RF), and to test the anticancer potential of these formulations. Methods ...
Caracterização físico-química de complexo de inclusão entre hidroximetilnitrofurazona e hidroxipropil-beta-ciclodextrina
(Química Nova, 2008-01-01) [Artigo]
Hydroxymethylnitrofurazone (NFOH) is a prodrug that is active against Trypanosoma cruzi. It however presents low solubility and high toxicity. Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) can be used as a drug-delivery ...
Interaction between nitroheterocyclic compounds with beta-cyclodextrins: Phase solubility and HPLC studies
(Journal of Pharmaceutical and Biomedical Analysis, 2008-08-05) [Artigo]
Chagas disease is a serious health problem for Latin America. Nitrofurazone (NF) and Hidroxymethylnitrofurazone (NFOH) are active against Trypanosoma cruzi. The effect of beta-cyclodextrin (beta-CD) and dimethyl-beta-cyclodextrin ...