Now showing items 1-6 of 6
Analysis of gene silencing mechanisms in laryngeal squamous cell carcinoma
(International Journal of Molecular Medicine, 2009-01-01) [Artigo]
Epigenetic Silencing of CRABP2 and MX1 in Head and Neck Tumors
(Neoplasia, 2009-12-01) [Artigo]
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease affecting the epithelium of the oral cavity, pharynx and larynx. Conditions of most patients are diagnosed at late stages of the disease, and no ...
Gene expression profiling reveals molecular marker candidates of laryngeal squamous cell carcinoma
(Oncology Reports, 2009-03-01) [Artigo]
Laryngeal squamous cell carcinoma is very common in head and neck cancer, with high mortality rates and poor prognosis. In this study, we compared expression profiles of clinical samples from 13 larynx tumors and 10 ...
Positive selection results in frequent reversible amino acid replacements in the G protein gene of human respiratory syncytial virus
(PLoS Pathogens, 2009-01-01) [Artigo]
Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter. Multiple ...
Quasispecies of hepatitis C virus genotype 1 and treatment outcome with Peginterferon and Ribavirin
(Infection, Genetics and Evolution, 2009-07-01) [Trabalho apresentado em evento]
The majority of patients with chronic hepatitis C fail to respond to antiviral therapy. The genetic basis of this resistance is unknown. The quasispecies nature of HCV may have an important implication concerning viral ...
RNA interference inhibits yellow fever virus replication in vitro and in vivo
(Virus Genes, 2009-04-01) [Artigo]
RNA interference (RNAi) is a process that is induced by double stranded RNA and involves the degradation of specific sequences of mRNA in the cytoplasm of the eukaryotic cells. It has been used as an antiviral tool against ...