Now showing items 1-5 of 5
Epigenetic Silencing of CRABP2 and MX1 in Head and Neck Tumors
(Neoplasia, 2009-12-01) [Artigo]
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease affecting the epithelium of the oral cavity, pharynx and larynx. Conditions of most patients are diagnosed at late stages of the disease, and no ...
Expression and purification of human respiratory syncytial virus recombinant fusion protein
(Protein Expression and Purification, 2008-12-01) [Artigo]
The Human Respiratory Syncytial Virus (HRSV) fusion protein (F) was expressed in Escherichia call BL21A using the pET28a vector at 37 degrees C. The protein was purified from the soluble fraction using affinity resin. The ...
Gene expression profiling reveals molecular marker candidates of laryngeal squamous cell carcinoma
(Oncology Reports, 2009-03-01) [Artigo]
Laryngeal squamous cell carcinoma is very common in head and neck cancer, with high mortality rates and poor prognosis. In this study, we compared expression profiles of clinical samples from 13 larynx tumors and 10 ...
Mutational analysis of the GAP-related domain of the neurofibromatosis type 1 gene in Brazilian NF1 patients
(Genetics and Molecular Biology, 2004-01-01) [Artigo]
Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder caused by mutations in the NF1 gene. In the present study, a total of 55 unrelated NF1 patients were screened for mutations in the GAP-related domain/GRD ...
RNA interference inhibits yellow fever virus replication in vitro and in vivo
(Virus Genes, 2009-04-01) [Artigo]
RNA interference (RNAi) is a process that is induced by double stranded RNA and involves the degradation of specific sequences of mRNA in the cytoplasm of the eukaryotic cells. It has been used as an antiviral tool against ...