Now showing items 11-20 of 22
Methylation profile of genes CDKN2A (p14 and p16), DAPK1, CDH1, and ADAM23 in head and neck cancer
(Cancer Genetics and Cytogenetics, 2007-02-01) [Artigo]
Hypermethylation in the promoter region has been associated with a loss of gene function that may give a selective advantage to neoplastic cells. In this study, the methylation pattern of genes CDKN2A (alias p14, p14(ARF), ...
Positive selection results in frequent reversible amino acid replacements in the G protein gene of human respiratory syncytial virus
(PLoS Pathogens, 2009-01-01) [Artigo]
Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter. Multiple ...
LHX6 is a sensitive methylation marker in head and neck carcinomas
(Oncogene, 2006-08-17) [Artigo]
Head and neck cancer remains a morbid and often fatal disease and at the present time few effective molecular markers have been identified. The purpose of the present work was to identify new molecular markers for head and ...
Mutational analysis of the GAP-related domain of the neurofibromatosis type 1 gene in Brazilian NF1 patients
(Genetics and Molecular Biology, 2004-01-01) [Artigo]
Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder caused by mutations in the NF1 gene. In the present study, a total of 55 unrelated NF1 patients were screened for mutations in the GAP-related domain/GRD ...
New molecular variants of hypothalamus-pituitary-gonad axis genes and their association with early puberty phenotype in Bos taurus indicus (Nellore)
(Livestock Science, 2008-04-01) [Artigo]
Endocrine system plays a major role in the control of reproductive functions which are regulated by the hypothalamus-pituitary-gonad axis and its interactions. FSH and LH receptor genes are expressed at the gonads and GnRH ...
RNA interference inhibits yellow fever virus replication in vitro and in vivo
(Virus Genes, 2009-04-01) [Artigo]
RNA interference (RNAi) is a process that is induced by double stranded RNA and involves the degradation of specific sequences of mRNA in the cytoplasm of the eukaryotic cells. It has been used as an antiviral tool against ...
The prevalence of human papillomavirus in the oropharynx in healthy individuals in a Brazilian population
(Journal of Medical Virology, 2006-05-01) [Artigo]
Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true ...
Routine libraries for pattern recognition in quasispecies.
(Genetics and molecular research : GMR, 2008-12-01) [Artigo]
The results obtained through biological research usually need to be analyzed using computational tools, since manual analysis becomes unfeasible due to the complexity and size of these results. For instance, the study of ...
Simultaneous infection by DENY 3 and SLEV in Brazil
(Journal of Clinical Virology, 2007-09-01) [Artigo]
A transcript finishing initiative for closing gaps in the human transcriptome
(Genome Research, 2004-07-01) [Artigo]
We report the results of a transcript finishing initiative, undertaken for the purpose of identifying and characterizing novel human transcripts, in which RT-PCR was used to bridge gaps between paired EST Clusters, mapped ...