Now showing items 1-10 of 13
Prostatic stromal cells of old gerbils respond to steroidal blockades creating a microenvironment similar to reactive stroma
(Biomedicine and Aging Pathology, 2011-04-01) [Artigo]
The present study examined the changes in prostatic stroma of old gerbils (18 months) submitted to orchiectomy associated or not with steroidal blockades. Animals were divided into six groups, all surgically castrated ...
Ionotropic but not metabotropic glutamatergic receptors in the Locus Coeruleus modulate the hypercapnic ventilatory response in unanesthetized rats
(FASEB Journal, 2013-04-01) [Resumo]
Structural and ultrastructural evidence for telocytes in prostate stroma
(Journal of Cellular and Molecular Medicine, 2013-03-01) [Artigo]
The prostate comprises a glandular epithelium embedded within a fibromuscular stroma. The stroma is a complex arrangement of cells and extracellular matrix (ECM) components in addition to growth factors, regulatory molecules, ...
Ionotropic but not metabotropic glutamatergic receptors in the locus coeruleus modulate the hypercapnic ventilatory response in unanaesthetized rats
(Acta Physiologica, 2013-05-01) [Artigo]
Aim: Central chemoreceptors are important to detect changes of CO2/H+, and the Locus coeruleus (LC) is one of the many putative central chemoreceptor sites. Here, we studied the contribution of LC glutamatergic receptors ...
Gestational and lactational exposition to Di-N-butyl-phthalate (DBP) increases inflammation and preneoplastic lesions in prostate of wistar rats after carcinogenic N-methyl-N-nitrosourea (MNU) plus testosterone protocol
(Environmental Toxicology, 2015-03-02) [Artigo]
In the present study, it was evaluated the susceptibility of prostatic lesions in male adult rats exposed to Di-N-butyl-phthalate during fetal and lactational periods and submitted to MNU plus testosterone carcinogenesis ...
MMP-2 and TIMP-2 in the prostates of male and female mongolian gerbils: Effects of hormonal manipulation
(Histology and Histopathology, 2011-11-01) [Artigo]
TIMPs in the prostates of male and female gerbils and evaluated the effects of testosterone on the expression of these enzymes. Ventral prostates from male gerbils that were either intact or had been castrated for 7 or 21 ...
MMP-2 and MMP-9 localization and activity in the female prostate during estrous cycle
(General and Comparative Endocrinology, 2011-09-15) [Artigo]
The gerbil female prostate undergoes morphological and physiological changes resulting from hormonal fluctuations that occur during the reproductive cycle. These repetitive cycles of glandular growth and regression are ...
A new proposed rodent model of chemically induced prostate carcinogenesis: Distinct time-course prostate cancer progression in the dorsolateral and ventral lobes
(Prostate, 2013-08-01) [Artigo]
Background. Characterization of novel rodent models for prostate cancer studies requires evaluation of either spontaneous and carcinogen-induced tumors as well as tumor incidence in different prostatic lobes. We propose a ...
Mast Cells and Ethanol Consumption: Interactions in the Prostate, Epididymis and Testis of UChB Rats
(American Journal of Reproductive Immunology, 2011-09-01) [Artigo]
ProblemAlcoholism has reached alarming proportions while fertility rates slowing in populations. The assessment of inflammatory effects with emphasis on the variation of the mast cells comparing ethanol chronic ingestion ...
Functional and Morphological Reproductive Aspects in Male Rats Exposed to Di-n-Butyl Phthalate (DBP) in Utero and During Lactation
(Journal of Toxicology and Environmental Health: Part A Current Issues, 2010-01-01) [Artigo]
The potential adverse reproductive effects, with emphasis on the epididymis, of in utero and lactational exposure to 100 mg/kg/d di-n-butyl phthalate (DBP) in adult male rat offspring were investigated. The fetal testis ...