Now showing items 1-6 of 6
Crystallization and preliminary X-ray diffraction analysis of a class II phospholipase D from Loxosceles intermedia venom
(Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2011-02-01) [Artigo]
Phospholipases D are the major dermonecrotic component of Loxosceles venom and catalyze the hydrolysis of phospholipids, resulting in the formation of lipid mediators such as ceramide-1-phosphate and lysophosphatidic acid ...
Purification, crystallization and preliminary X-ray diffraction analysis of a class P-III metalloproteinase (BmMP-III) from the venom of Bothrops moojeni
(Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012-10-01) [Artigo]
Snake-venom metalloproteinases (SVMPs) comprise a family of haemostatically active toxins which can cause haemorrhage, coagulopathy, inhibition of platelet aggregation and inflammatory response. These effects are attributed ...
Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins
(Toxicon, 2014-06-01) [Artigo]
The Loxosceles genus spiders (the brown spiders) are encountered in all the continents, and the clinical manifestations following spider bites include skin necrosis with gravitational lesion spreading and occasional systemic ...
Crystal structure of mature 2S albumin from Moringa oleifera seeds
(Biochemical And Biophysical Research Communications, 2015-10-23) [Artigo]
2S albumins, the seed storage proteins, are the primary sources of carbon and nitrogen and are involved in plant defense. The mature form of Moringa oleifera (M. oleifera), a chitin binding protein isoform 3-1 (mMo-CBP3-1) ...
Crystallization and preliminary X-ray diffraction analysis of a novel sphingomyelinase D from Loxosceles gaucho venom
(Acta Crystallographica Section F-structural Biology Communications, 2014-10-01) [Artigo]
Brown spider envenomation results in dermonecrosis, intravascular coagulation, haemolysis and renal failure, mainly owing to the action of sphingomyelinases D (SMases D), which catalyze the hydrolysis of sphingomyelin to ...
Crystallization and preliminary X-ray diffraction studies of an L-amino-acid oxidase from Lachesis muta venom
(Acta Crystallographica Section F-structural Biology Communications, 2014-11-01) [Artigo]
Snake-venom proteins form multi-component defence systems by the recruitment and rapid evolution of nonvenomous proteins and hence serve as model systems to understand the structural modifications that result in toxicity. ...