Now showing items 1-6 of 6
Immune Response Against Sporothrix schenckii in TLR-4-Deficient Mice
(Mycopathologia, 2012-07-01) [Artigo]
For many fungal diseases, macrophages are the major cell population implicated in host protection, primarily by their ability to eliminate the invading fungal pathogen through phagocytosis. In sporotrichosis, this remains ...
Immunological response in mice bearing LM3 breast tumor undergoing Pulchellin treatment
(BMC Complementary and Alternative Medicine, 2012-07-24) [Artigo]
Background: Ribosome-inactivating proteins (RIP) have been studied in the search for toxins that could be used as immunotoxins for cancer treatment. Pulchellin, a type 2 RIP, is suggested to induce immune responses that ...
Impact of sub-inhibitory concentrations of amoxicillin on helicobacter pylori virulence factors
(World Journal of Pharmaceutical Research, 2014) [Artigo]
Helicobacter pylori are etiological factor of human acute and chronic gastritis. Critical host responses that influence the progression to H. pylori-induced carcinogenesis include gastric inflammation. This study was ...
Dectin-1 expression by macrophages and related antifungal mechanisms in a murine model of Sporothrix schenckii sensu stricto systemic infection
(Microbial Pathogenesis, 2017-09-01) [Artigo]
The available information about the role of Dectin-1 in sporotrichosis is scarce. Hence, we aimed to assess Dectin-1 expression by macrophages and the activation of some related antifungal mechanisms during the Sporothrix ...
Sporothrix brasiliensis induces a more severe disease associated with sustained Th17 and regulatory T cells responses than Sporothrix schenckii sensu stricto in mice
(Fungal Biology, 2018-01-01) [Artigo]
Little is known about the differences in the CD4+ T-cell response induced by Sporothrix schenckii and Sporothrix brasiliensis, the most virulent species that cause sporotrichosis. Here, the helper (Th) and regulatory T ...
Involvement of major components from sporothrix schenckii cell wall in the caspase-1 activation, nitric oxide and cytokines production during experimental sporotrichosis
(Mycopathologia, 2015-02-01) [Artigo]
Sporotrichosis is a chronic infection caused by the dimorphic fungus Sporothrix schenckii, involving all layers of skin and the subcutaneous tissue. The role of innate immune toll-like receptors 2 and 4 in the defense ...