Now showing items 21-40 of 696

  • New compounds of Siolmatra brasiliensis and inhibition of in vitro protein glycation damage

    dos Santos, Carlos Henrique Corrêa; Talpo, Tassiana Cristina Autor UNESP; Motta, Bruno Pereira Autor UNESP; Kaga, Anderson Kiyoshi Autor UNESP; Baviera, Amanda Martins Autor UNESP; Castro, Rosane Nora; da Silva, Virgínia Cláudia; de Sousa-Junior, Paulo Teixeira; Wessjohann, Ludger; de Carvalho, Mário Geraldo (Fitoterapia, 2019) [Artigo]
    Twenty compounds were isolated from the hydroethanolic extract of the stems of Siolmatra brasiliensis, five flavonoids, two lignans, one glucosyl phytosterol, seven nor-cucurbitacins, one new phenolic derivative named ...
  • Phagolysosomal activity of macrophages in Nile tilapia (Oreochromis niloticus) infected in vitro by Aeromonas hydrophila: Infection and immunotherapy

    Fernandes, Dayanne C. Autor UNESP; Eto, Silas F. Autor UNESP; Moraes, Alessandra C. Autor UNESP; Prado, Ed Johnny R. Autor UNESP; Medeiros, Andrea S.R. Autor UNESP; Belo, Marco A.A. Autor UNESP; Samara, Samir I. Autor UNESP; Costa, Paulo I. Autor UNESP; Pizauro, João M. Autor UNESP (Fish and Shellfish Immunology, 2019) [Artigo]
    The biochemical mechanisms involved in phagocytosis and the intracellular survival of Aeromonas hydrophila (Ah) in host macrophages (MΦs) are complex processes that affect infection success or failure. Thus, in the present ...
  • Effective treatment and decolonization of a dog infected with carbapenemase (VIM-2)-producing Pseudomonas aeruginosa using probiotic and photodynamic therapies

    Sellera, Fábio P.; Fernandes, Miriam R.; Sabino, Caetano P.; de Freitas, Laura M. Autor UNESP; da Silva, Luciano C.B.A.; Pogliani, Fabio C.; Ribeiro, Martha S.; Hamblin, Michael R.; Lincopan, Nilton (Veterinary Dermatology, 2019) [Artigo]
    Background: Carbapenem-resistant bacterial infections are a critical problem in veterinary medicine with limited treatment options. Objective: To describe effective probiotic and photodynamic therapy of a dog with gut ...
  • In vitro inhibition of protein glycation and advanced glycation end products formation by hydroethanolic extract and two fractions of Simaba trichilioides roots

    Motta, Bruno Pereira Autor UNESP; Kaga, Anderson Kiyoshi Autor UNESP; Oliveira, Juliana Oriel Autor UNESP; Inacio, Maiara Destro Autor UNESP; da Silva, Cledson Ferreira; de Sousa Junior, Paulo Teixeira; Brunetti, Iguatemy Lourenço Autor UNESP; Baviera, Amanda Martins Autor UNESP (Natural Product Research, 2018) [Artigo]
    Long-term hyperglycemia maintenance is responsible for increased protein glycation and formation of advanced glycation end products (AGEs), both are associated with the onset of diabetes mellitus complications. Efforts ...
  • Neisseria meningitidis serogroup B lipopolysaccharides induce a lower pro-inflammatory effect within the proteoliposome used in Cuban anti-meningococcal vaccines

    Pérez, O.; Graham, S.; Lastre, M.; Ellis, C. D.; Pupo, R. R.; Tellez-Martínez, D. Autor UNESP; Batista-Duharte, A. Autor UNESP (Vacunas, 2018) [Artigo]
    Neisseria meningitidis outer membrane vesicles or proteoliposomes (PLs) have been used as vaccines and adjuvants. Despite the presence of potentially toxic amounts of lipopolysaccharide (LPS), they have been shown to be ...
  • Sporothrix schenckii cell wall proteins-stimulated bmdcs are able to induce a th1-prone cytokine profile in vitro

    Quinello, Camila Autor UNESP; Ferreira, Lucas Souza Autor UNESP; Picolli, Isabella Autor UNESP; Loesch, Maria Luiza Autor UNESP; Portuondo, Deivys Leandro Autor UNESP; Batista-Duharte, Alexander Autor UNESP; Carlos, Iracilda Zeppone Autor UNESP (Journal of Fungi, 2018) [Artigo]
    Sporotrichosis is a subcutaneous mycosis affecting humans and other animals. The disease can be acquired by accidental inoculation of the fungus through the skin or through the respiratory system. Sporotrichosis can also ...
  • Repeated exposition to mercury (II) chloride enhances susceptibility to s. schenckii sensu stricto infection in mice

    Batista-Duharte, Alexander Autor UNESP; Téllez-Martínez, Damiana Autor UNESP; Jellmayer, Juliana Aparecida Autor UNESP; Fuentes, Deivys Leandro Portuondo Autor UNESP; Polesi, Marisa Campos Autor UNESP; Baviera, Amanda Martins Autor UNESP; Carlos, Iracilda Zeppone Autor UNESP (Journal of Fungi, 2018) [Artigo]
    Sporotrichosis is a subcutaneous mycosis that has re-emerged in several tropical and subtropical regions over the last decades. Growing findings suggest that the interplay of host, pathogen, and environment has a determinant ...
  • High-fat diet increases respiratory frequency and abdominal expiratory motor activity during hypercapnia

    Speretta, Guilherme F. Autor UNESP; Lemes, Eduardo Autor UNESP; Vendramini, Regina C. Autor UNESP; Menani, José V. Autor UNESP; Zoccal, Daniel B. Autor UNESP; Colombari, Eduardo Autor UNESP; Colombari, Débora S.A. Autor UNESP; Bassi, Mirian Autor UNESP (Respiratory Physiology and Neurobiology, 2018) [Artigo]
    Breathing disorders are commonly observed in association with obesity. Here we tested whether high-fat diet (HFD) impairs the chemoreflex ventilatory response. Male Holtzman rats (300–320 g) were fed with standard chow ...
  • Fungal biofilms and polymicrobial diseases

    Costa-Orlandi, Caroline B. Autor UNESP; Sardi, Janaina C. O.; Pitangui, Nayla S. Autor UNESP; de Oliveira, Haroldo C. Autor UNESP; Scorzoni, Liliana Autor UNESP; Galeane, Mariana C. Autor UNESP; Medina-Alarcón, Kaila P. Autor UNESP; Melo, Wanessa C. M. A. Autor UNESP; Marcelino, Mônica Y. Autor UNESP; Braz, Jaqueline D. Autor UNESP et al. (Journal of Fungi, 2017) [Resenha]
    Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized communities that are resistant to ...
  • In vitro activities of glycoalkaloids from the Solanum lycocarpum against Leishmania infantum

    Clementino, Leandro da Costa Autor UNESP; Velásquez, Angela Maria Arenas Autor UNESP; Passalacqua, Thais Gaban Autor UNESP; de Almeida, Leticia Autor UNESP; Graminha, Marcia A.S. Autor UNESP; Martins, Gilmarcio Z.; Salgueiro, Lígia; Cavaleiro, Carlos; Sousa, Maria do Céu; Moreira, Raquel R.D. Autor UNESP (Brazilian Journal of Pharmacognosy, 2018) [Artigo]
    Leishmania infantum is an etiologic agent of visceral leishmaniasis. This disease is a neglected disease that can be fatal if not treated and additionally, the few therapeutic option present several drawbacks, including ...
  • Chemopreventive role of Copaifera reticulata Ducke oleoresin in colon carcinogenesis

    Senedese, Juliana Marques; Rinaldi-Neto, Francisco; Furtado, Ricardo Andrade; Nicollela, Heloiza Diniz; Ribeiro de Souza, Larissa Daniela; Ribeiro, Arthur Barcelos; Ferreira, Lucas Souza Autor UNESP; Magalhaes, Georgia Mode; Carlos, Iracilda Zeppone Autor UNESP; Mangabeira da Silva, Jonas Joaquim et al. (Biomedicine & Pharmacotherapy, 2019) [Artigo]
    In Brazilian folk medicine, copaiba oleoresin is widely known for its therapeutic activity, especially its wound healing and anti-inflammatory actions. Considering the relationship between inflammatory processes and ...
  • Geraniol and linalool anticandidal activity, genotoxic potential and embryotoxic effect on zebrafish

    Singulani, Junya L. Autor UNESP; Pedroso, Reginaldo S.; Ribeiro, Arthur B.; Nicolella, Heloiza D.; Freitas, Karoline S.; Damasceno, Jacqueline L.; Vieira, Tatiana M.; Crotti, Antonio E. M.; Tavares, Denise C.; Martins, Carlos H. G. et al. (Future Microbiology, 2018) [Artigo]
    Aim: Geraniol and linalool are major constituents of the essential oils of medicinal plants. Materials & methods: Antifungal activity of geraniol and linalool were evaluated against five Candida species. The genotoxicity ...
  • Miniaturized wireless system for hepatitis C detection

    Costa, Joao Paulo; Bastos, Wagner; Costa, Paulo Autor UNESP; Longo, Elson; Zaghete, Maria Autor UNESP; Carmo, Joao Paulo (Abstracts Of Papers Of The American Chemical Society, 2019) [Resumo]
  • Isolation and identification of polymethoxylated flavones metabolites in rat urine and its evaluation on hepatic lipoprotein secretion

    Goncalves, Danielle Autor UNESP; Manthey, John; Costa, Paulo Autor UNESP; Cesar, Thais (Abstracts Of Papers Of The American Chemical Society, 2019) [Resumo]
  • A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats

    Ceolin, Patricia; De Franca, Suelem A.; Froelich, Mendalli; Dos Santos, Maisa P.; Pereira, Mayara P.; Queiroz, Thais S.; Da Silva, Flavia H. S.; Lisboa, Patricia C.; Andrade, Claudia M. B.; Baviera, Amanda M. Autor UNESP et al. (Anais Da Academia Brasileira De Ciencias, 2019) [Artigo]
    The aim of this study was investigate the effects of a low-protein, high-carbohydrate (LPHC) diet introduced to rats soon after weaning. The animals were distributed in the following groups: LPHC45: fed an LPHC diet ...
  • Chemical composition and biological properties of Ipomoea procumbens

    Batiga, Saadia; Valli, Marilia Autor UNESP; Zeraik, Maria L.; Fraige, Karina Autor UNESP; Leme, Gabriel M. Autor UNESP; Pitangui, Nayla S. Autor UNESP; Almeida, Ana Marisa F. Autor UNESP; Michel, Sylvie; Young, Maria Claudia M.; Bolzani, Vanderlan S. Autor UNESP (Revista Brasileira De Farmacognosia-brazilian Journal Of Pharmacognosy, 2019) [Artigo]
    Natural products have been the most valuable source of chemical compounds in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of ...
  • Antileishmanial activity of the Antarctic red algae Iridaea cordata (Gigartinaceae; Rhodophyta)

    Rangel, Karen C.; Debonsi, Hosana M.; Clementino, Leandro C. Autor UNESP; Graminha, Marcia A. S. Autor UNESP; Vilela, Leonardo Z.; Colepicolo, Pio; Gaspar, Lorena R. (Journal Of Applied Phycology, 2019) [Artigo]
    Leishmaniasis is considered a neglected disease and affects billions around the world, currently presenting few therapeutic options, which makes the development of new antileishmanial drugs urgent. Secondary metabolites ...
  • Nitric Oxide Releasing Nanoparticles as a Strategy to Improve Current Onychomycosis Treatments

    Costa-Orlandi, Caroline B. Autor UNESP; Mordorski, Breanne; Baltazar, Ludmila M.; Mendes-Giannini, Maria Jose S. Autor UNESP; Friedman, Joel M.; Nosanchuk, Joshua D.; Friedman, Adam J. (Journal Of Drugs In Dermatology, 2018) [Artigo]
    Topical antimicrobials are the ideal mode of onychomycosis treatment for efficient drug delivery and avoidance of sytemic effects associated with oral medications. However, high treatment costs, tissue penetration limitations, ...
  • SYNTHESIS; CHARACTERIZATION AND CYTOTOXIC ACTIVITY EVALUATION OF CYCLOPALLADATED COMPOUNDS CONTAINING ORTHOMETALLATED BENZALDEHYDEOXIME AND ETHYLENETHIOUREA AS LIGANDS

    Thomazella, Nothalia A. Autor UNESP; Lemos, Sahra C. Autor UNESP; Souza, Ronan F. F. de Autor UNESP; Souza, Rodrigo A. de Autor UNESP; Mauro, Antonio E. Autor UNESP; Carlos, Iracilda Z. Autor UNESP; Netto, Adelino V. G. Autor UNESP (Quimica Nova, 2018) [Artigo]
    The halide bridge cleavage reaction of the [Pd(C-2,N-bzox)(mu-Cl)](2). compound (bzox = benzaldehydeoxime) with ethylenethiourea (L) in the 1:2 molar ratio at room temperature yielded the cyclopalladated compound ...
  • Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation

    Melo, Thais Regina Ferreira de Autor UNESP; Kumkhaek, Chutima; Fernandes, Guilherme Felipe Dos Santos Autor UNESP; Lopes Pires, Maria Elisa; Chelucci, Rafael Consolin Autor UNESP; Barbieri, Karina Pereira Autor UNESP; Coelho, Fernanda Autor UNESP; Capote, Ticiana Sidorenko de Oliveira Autor UNESP; Lanaro, Carolina; Carlos, Iracilda Zeppone Autor UNESP et al. (European journal of medicinal chemistry, 2018) [Artigo]
    N-oxide derivatives 5(a-b), 8(a-b), and 11(a-c) were designed, synthesized and evaluated in vitro and in vivo as potential drugs that are able to ameliorate sickle cell disease (SCD) symptoms. All of the compounds demonstrated ...