Now showing items 1-10 of 16
Histopathological changes in the gill, liver and kidney of pacu (Piaractus mesopotamicus, Holmberg, 1887) exposed to various concentrations of trichlorfon
(Journal of Applied Ichthyology, 2009-02-01) [Artigo]
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth.
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2009-05-01) [Artigo]
Dimorphandra mollis Benth., Compositae, false barbatimão, has been used topically as a healing, astringent and antibacterial. In this study, antibacterial activity was verified on liquid soap containing glycolic extract ...
Corticosterone levels in mice exposed to different types of elevated plus-maze: influence of nociceptive stimulation
(European Neuropsychopharmacology, 2009-09-01) [Artigo]
Exposure to acute restraint stress reinstates nicotine-induced place preference in rats
(Behavioural Pharmacology, 2009-02-01) [Artigo]
Tobacco addiction is associated with high rates of relapse to drug use even after prolonged periods of abstinence. Relapse can occur upon reexposure to the drug of abuse, exposure to stress or to stimuli associated with ...
Blockade of fear-induced antinociception with intra-amygdala infusion of midazolam: Influence of prior test experience
(Brain Research, 2009-10-06) [Artigo]
Intra-amygdala infusion of midazolam, a benzodiazepine receptor agonist, produces anxiolytic-like effects in mice when first exposed to the elevated plus-maze (EPM) and blocks antinociception induced in mice confined in ...
Synthesis, ex Vivo and in Vitro Hydrolysis Study of an Indoline Derivative Designed as an Anti-Inflammatory with Reduced Gastric Ulceration Properties
(Molecules, 2009-09-01) [Artigo]
The compound 1-(2,6-dichlorophenyl)indolin-2-one (1), planned as a pro-drug of diclofenac (2), was easily synthesized in 94% yield by an intramolecular reaction in the presence of coupling agent (i.e., EDC). Compound 1 ...
Cocaine induces cell death and activates the transcription nuclear factor kappa-b in pc12 cells
(Molecular Brain, 2009-01-01) [Artigo]
Cocaine is a worldwide used drug and its abuse is associated with physical, psychiatric and social problems. The mechanism by which cocaine causes neurological damage is very complex and involves several neurotransmitter ...
Identificação de diterpenos clerodânicos em diferentes órgãos de Casearia sylvestris Swartz
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2009-09-01) [Artigo]
Casearia sylvestris Swartz (Salicaceae) is a tree or shrub distributed widely in Brazil, where it is used in popular medicine. Several bioactive clerodane diterpenes typical of Casearia have been isolated from this species ...
Amphetamine- and nicotine-induced cross-sensitization in adolescent rats persists until adulthood
(Addiction Biology, 2009-07-01) [Artigo]
Nicotine and psychostimulants are often abused in combination and drug abuse often begins during adolescence and can have long-term consequences. Behavioral sensitization has been suggested as an animal model of neuroplasticity ...
Anxiolytic-like effects produced by bilateral lesion of the periaqueductal gray in mice: Influence of concurrent nociceptive stimulation
(Behavioural Brain Research, 2009-11-05) [Artigo]
Threatening situations (e.g., exposure to an elevated plus-maze with four open arms - oEPM) induce behavioral and neurovegetative responses generally accompanied by antinociception animals. The midbrain periaqueductal gray ...