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Modulation of miR-26a-5p and miR-15b-5p exosomal expression associated with clopidogrel-induced hepatotoxicity in HepG2 cells
(Frontiers in Pharmacology, 2017-12-12) [Artigo]
Clopidogrel is an essential antiplatelet drug used to prevent thrombosis complications associated with atherosclerosis. However, hepatotoxicity is a potential adverse effect related to clopidogrel therapy. Exosome-derived ...
Exposure to BDE-153 induces autophagy in HepG2 cells
(Toxicology in Vitro, 2017-08-01) [Artigo]
Autophagy is a pro-survival process that occurs under stressful “life-threatening” conditions. This process clears the cells of damaged organelles, long-lived proteins, and/or misfolded proteins. Under stressful conditions, ...