Publicação: Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
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Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.
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Direct acting-antiviral, Hepatitis C virus, Resistant mutants, Therapy
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Inglês
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American Journal of Infectious Diseases, v. 10, n. 4, p. 182-186, 2014.
