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SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS

dc.contributor.authorSilva, A. E.
dc.contributor.authorManzato, A. J.
dc.contributor.authorVarellagarcia, M.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:28:18Z
dc.date.available2014-05-20T15:28:18Z
dc.date.issued1993-03-01
dc.description.abstractLymphocytes from beta thalassaemia heterozygote patients, with normal levels of plasma folic acid cultured for 72 h in a folate rich medium, were not found to contain increased rates of sister chromatid exchanges (SCE). A wide intra and interindividual variability was found in both thalassaemic and control groups and methodological and biological factors, such as types of peripheral lymphocytes, sex, age, and smoking, alcohol and coffee drinking, as well as dietary habits, are possibly responsible for these variations.en
dc.description.affiliationUNESP,LETRAS & CIENCIAS EXATAS,INST BIOCIENCIAS,DEPT BIOL,BR-15054 S JOSE RIO P,SP,BRAZIL
dc.description.affiliationUnespUNESP,LETRAS & CIENCIAS EXATAS,INST BIOCIENCIAS,DEPT BIOL,BR-15054 S JOSE RIO P,SP,BRAZIL
dc.format.extent203-210
dc.identifierhttp://www.gmb.org.br/Revistas/V16/v16a019.pdf
dc.identifier.citationRevista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 16, n. 1, p. 203-210, 1993.
dc.identifier.fileWOSA1993KU77900019.pdf
dc.identifier.issn0100-8455
dc.identifier.urihttp://hdl.handle.net/11449/38132
dc.identifier.wosWOS:A1993KU77900019
dc.language.isoeng
dc.publisherSoc Brasil Genetica
dc.relation.ispartofRevista Brasileira de Genética
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleSISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELSen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/bjg/paboutj.htm
dcterms.rightsHolderSoc Brasil Genetica
dspace.entity.typePublication
unesp.author.lattes2503906319038306[1]
unesp.author.orcid0000-0003-1491-8878[1]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências Letras e Ciências Exatas, São José do Rio Pretopt
unesp.departmentBiologia - IBILCEpt

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