Structure and Biogenesis of Roussoellatide, a Dichlorinated Polyketide from the Marine-Derived Fungus Roussoella sp DLM33
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Undergraduate course
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Amer Chemical Soc
American Chemical Society (ACS)
American Chemical Society (ACS)
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Article
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Abstract
The structure of the fungal metabolite roussoellatide (1) has been established by spectroscopic and X-ray diffraction analyses. Results from feeding experiments with [1-C-13]acetate, [2-C-13]acetate, and [1,2-C-13]acetate were consistent with a biosynthetic pathway to the unprecedented skeleton of 1 involving Favorskii rearrangements in separate pentaketides, subsequently joined via an intermolecular Diels-Alder reaction.
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English
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Organic Letters. Washington: Amer Chemical Soc, v. 17, n. 21, p. 5152-5155, 2015.
