Publicação:
Initial structural analysis of an alpha(4)beta(4) C-type lectin from the venom of Crotalus durissus terrificus

Página do item simplificado
dc.contributor.authorMurakami, M. T.
dc.contributor.authorWatanabe, L.
dc.contributor.authorGava, L. M.
dc.contributor.authorZela, S. P.
dc.contributor.authorCintra, ACO
dc.contributor.authorArni, R. K.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T14:02:19Z
dc.date.available2014-05-20T14:02:19Z
dc.date.issued2003-10-01
dc.description.abstractConvulxin, an alphabeta C-type lectin, is a potent platelet activator isolated from the venom of the South American rattlesnake Crotalus durissus terrificus. It is a 26.5 kDa alphabeta heterodimer consisting of two homologous disulfide-linked chains. The crystals belong to space group I4, with unit-cell parameters a = b = 131.61, c = 121.85 Angstrom, and diffraction data were collected to 2.7 Angstrom. The structure was solved by molecular replacement and the asymmetric unit contains two alphabeta heterodimers, each of which forms a disulfide-linked cyclic alpha(4)beta(4) tetramer in the unit cell. These alpha(4)beta(4) tetramers are stacked to form a large solvent channel.en
dc.description.affiliationUNESP, IBILCE, Dept Phys, BR-15005400 Sao Jose do Rio Preto, SP, Brazil
dc.description.affiliationUSP, Fac Ciências Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP, Brazil
dc.description.affiliationUnespUNESP, IBILCE, Dept Phys, BR-15005400 Sao Jose do Rio Preto, SP, Brazil
dc.format.extent1813-1815
dc.identifierhttp://dx.doi.org/10.1107/S0907444903016202
dc.identifier.citationActa Crystallographica Section D-biological Crystallography. Copenhagen: Blackwell Munksgaard, v. 59, p. 1813-1815, 2003.
dc.identifier.doi10.1107/S0907444903016202
dc.identifier.issn0907-4449
dc.identifier.lattes9162508978945887
dc.identifier.orcid0000-0003-2460-1145
dc.identifier.urihttp://hdl.handle.net/11449/21962
dc.identifier.wosWOS:000185451200018
dc.language.isoeng
dc.publisherBlackwell Munksgaard
dc.relation.ispartofActa Crystallographica Section D: Biological Crystallography
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleInitial structural analysis of an alpha(4)beta(4) C-type lectin from the venom of Crotalus durissus terrificusen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderBlackwell Munksgaard
dspace.entity.typePublication
unesp.author.lattes9162508978945887[6]
unesp.author.orcid0000-0003-2460-1145[6]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Pretopt
unesp.departmentFísica - IBILCEpt

Arquivos

Licença do Pacote

Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

São José do Rio Preto - IBILCE - Instituto de Biociências, Letras e Ciências Exatas