Acetylcholinesterase Inhibitory Pyridine Alkaloids of the Leaves of Senna multijuga
Loading...
Files
External sources
External sources
Date
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Amer Chemical Soc
Type
Abstract
Access right
Acesso restrito
Files
External sources
External sources
Abstract
Two unusual pyridine alkaloids, 7'-multijuguinone (1) and 12'-hydroxy-7'-multijuguinone none (2), were isolated front the leaves of Senna multijuga, together with the known flavonoid rutin. The structures of the new alkaloids were established oil the basis of spectroscopy data interpretation. Compounds I and 2 exhibited moderate in vitro acetylcholinesterase (AChE) inhibitory activity, in comparison With the standard compound physostiomine.
Description
Keywords
Language
English
Citation
Journal of Natural Products. Washington: Amer Chemical Soc, v. 73, n. 3, p. 482-484, 2010.
