Brown Recluse Spider Venom: Proteomic Analysis and Proposal of a Putative Mechanism of Action
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Undergraduate course
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Bentham Science Publ Ltd
Type
Article
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Abstract
Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures.
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Keywords
Proteomic analysis, spider venom, MudPIT, mass spectrometry, mechanism of action
Language
English
Citation
Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 8, p. 933-943, 2009.
