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Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs

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dc.contributor.authorGoloni-Bertollo, E. M. [UNESP]
dc.contributor.authorTajara, E. H. [UNESP]
dc.contributor.authorManzato, A. J. [UNESP]
dc.contributor.authorVarella-Garcia, M.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFaculdade de Medicina de São José do Rio Preto (Famerp)
dc.date.accessioned2014-05-20T15:19:38Z
dc.date.available2014-05-20T15:19:38Z
dc.date.issued1992-01-01
dc.description.abstractChromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals were compared with 15 nurses working in other hospital units and to a control sample matched by sex and age. This points to the need for emphasizing protective measures in the handling of anti-neoplastic agents.en
dc.description.affiliationUniversidade Estadual Paulista (UNESP), Departamento de Biologia, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil
dc.description.affiliationUniversidade Estadual Paulista (UNESP), Departamento Ciências da Computação e Estatística, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil
dc.description.affiliationFaculdade de Medicina de São José do Rio Preto, Departamento Ciências Biológicas, São José do Rio Presto,SP, Brazil
dc.description.affiliationUnespUniversidade Estadual Paulista (UNESP), Departamento de Biologia, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil
dc.description.affiliationUnespUniversidade Estadual Paulista (UNESP), Departamento Ciências da Computação e Estatística, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil
dc.format.extent341-344
dc.identifierhttp://dx.doi.org/10.1002/ijc.2910500302
dc.identifier.citationInternational Journal of Cancer. New York: Wiley-liss, v. 50, n. 3, p. 341-344, 1992.
dc.identifier.doi10.1002/ijc.2910500302
dc.identifier.issn0020-7136
dc.identifier.scopus2-s2.0-0026565666
dc.identifier.urihttp://hdl.handle.net/11449/130409
dc.identifier.wosWOS:A1992HC03000001
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofInternational Journal of Cancer
dc.relation.ispartofjcr7.360
dc.relation.ispartofsjr3,152
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAntineoplastic agent
dc.subjectChromosome aberration
dc.subjectClinical article
dc.subjectControlled study
dc.subjectFemale
dc.subjectHuman
dc.subjectHuman cell
dc.subjectLymphocyte
dc.subjectNurse
dc.subjectPriority journal
dc.subjectSide effect
dc.subjectSister chromatid exchange
dc.subjectAdult
dc.subjectAntineoplastic Agents
dc.subjectChromosome Aberrations
dc.subjectFemale
dc.subjectHuman
dc.subjectNurses
dc.subjectNurses' Aides
dc.subjectOccupational Exposure
dc.subjectSister Chromatid Exchange
dc.subjectSupport, Non-U.S. Gov't
dc.subjectSupport, U.S. Gov't, P.H.S.
dc.titleSister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugsen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências Letras e Ciências Exatas, São José do Rio Pretopt
unesp.departmentBiologia - IBILCEpt
unesp.departmentCiências da Computação e Estatística - IBILCEpt

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São José do Rio Preto - IBILCE - Instituto de Biociências, Letras e Ciências Exatas