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New bioactive metabolites produced by Phomopsis cassiae, an endophytic fungus in Cassia spectabilis

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dc.contributor.authorSilva, Geraldo H. [UNESP]
dc.contributor.authorAraújo, Angela Regina [UNESP]
dc.contributor.authorTelesa, Helder L. [UNESP]
dc.contributor.authorTrevisana, Henrique C. [UNESP]
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorYoung, Maria C. M.
dc.contributor.authorPfenning, Ludwig H.
dc.contributor.authorEberlind, Marcos N.
dc.contributor.authorHaddad, Renato
dc.contributor.authorCosta-Netoe, Claudio M.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Lavras (UFLA)
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionInstituto de Botânica
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:21:40Z
dc.date.available2014-05-27T11:21:40Z
dc.date.issued2005-11-01
dc.description.abstractTwo new metabolites, ethyl 2,4-dihydroxy-5,6-dimethylbenzoate (1) and phomopsilactone (2) were isolated from Phomopsis cassiae, an endophytic fungus in Cassia spectabilis. Their structures were elucidated by 1D and 2D NMR, MS and IR spectral data. Compounds 1 and 2 displayed strong antifungal activity against the phytopatogenic fungi Cladosporium cladosporioides and C. sphaerospermum, as well as cytotoxicity against human cervical tumor cell line (HeLa), in in vitro assays. ©2005 Sociedade Brasileira de Química.en
dc.description.affiliationInstituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara-SP
dc.description.affiliationDepartamento de Fitopatologia Universidade Federal de Lavras, CP 37, 37200-000 Lavras-MG
dc.description.affiliationInstituto de Química Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas-SP
dc.description.affiliationSeção de Fisiologia e Bioquímica de Plantas Instituto de Botânica, CP 4005, 97010-051 São Paulo-SP
dc.description.affiliationDepartamento de Bioquímica e Imunologia Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo, 14049-900 Ribeirão Preto-SP
dc.description.affiliationUnespInstituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara-SP
dc.format.extent1463-1466
dc.identifierhttp://dx.doi.org/10.1590/S0103-50532005000800029
dc.identifier.citationJournal of the Brazilian Chemical Society, v. 16, n. 6 B, p. 1463-1466, 2005.
dc.identifier.doi10.1590/S0103-50532005000800029
dc.identifier.file2-s2.0-30844445632.pdf
dc.identifier.issn0103-5053
dc.identifier.lattes0037579054083160
dc.identifier.lattes4484083685251673
dc.identifier.orcid0000-0001-7616-9652
dc.identifier.scieloS0103-50532005000800029
dc.identifier.scopus2-s2.0-30844445632
dc.identifier.urihttp://hdl.handle.net/11449/68473
dc.identifier.wosWOS:000234078700029
dc.language.isoeng
dc.relation.ispartofJournal of the Brazilian Chemical Society
dc.relation.ispartofjcr1.444
dc.relation.ispartofsjr0,357
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAntifungal activity
dc.subjectCassia spectabilis
dc.subjectCytotoxic metabolites
dc.subjectEndophytic fungi
dc.subjectPhomopsis cassiae
dc.titleNew bioactive metabolites produced by Phomopsis cassiae, an endophytic fungus in Cassia spectabilisen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/jbchs/iaboutj.htm
dspace.entity.typePublication
unesp.author.lattes0037579054083160[2]
unesp.author.lattes4484083685251673
unesp.author.orcid0000-0001-7616-9652[2]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Orgânica - IQARpt

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