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Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora

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dc.contributor.authorBatista, Andrea N. de L. [UNESP]
dc.contributor.authorColombo, Renata [UNESP]
dc.contributor.authorPascoli, Inara C. de [UNESP]
dc.contributor.authorTeles, Helder L. [UNESP]
dc.contributor.authorSilva, Geraldo H. [UNESP]
dc.contributor.authorBomfim, Giovanni C. C. [UNESP]
dc.contributor.authorBurgos, Rosilene C. R. [UNESP]
dc.contributor.authorCavalheiro, Alberto José [UNESP]
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorSilva, Dulce Helena Siqueira [UNESP]
dc.contributor.authorReimberg, Maria Célia H.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionAnidro do Brasil Extrações Ltda
dc.date.accessioned2014-05-20T14:20:57Z
dc.date.available2014-05-20T14:20:57Z
dc.date.issued2011-06-01
dc.description.abstractMyrcia uniflora Barb. Rodr., Myrtaceae, popularly known as pedra-hume-caá in Brazil, is sold as dry extracts in capsules or as tinctures for the treatment of diabetes mellitus. Previous phytochemical studies on this species described the occurrence of the flavonoids mearnsitrin and myricitrin. In the present study, the chromatographic profiles of M. uniflora leaves and commercial extracts were determined using HPLC-PAD. Myricitrin was used as an external standard in the development and validation of the HPLC method. The proposed method is simple, rapid and reliable and can be successfully applied in industry for standardization of herbs and phytomedicines commercialised in Brazil as pedra-hume-caá.en
dc.description.affiliationUniversidade Estadual Paulista Instituto de Química Departamento de Química Orgânica
dc.description.affiliationAnidro do Brasil Extrações Ltda
dc.description.affiliationUnespUniversidade Estadual Paulista Instituto de Química Departamento de Química Orgânica
dc.description.sponsorshipAnidro do Brasil Extracoes Ltda (Botucatu, SP, Brazil)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdCNPq: 500185/2006-9
dc.format.extent402-406
dc.identifierhttp://dx.doi.org/10.1590/S0102-695X2011005000066
dc.identifier.citationRevista Brasileira de Farmacognosia. Sociedade Brasileira de Farmacognosia, v. 21, n. 3, p. 402-406, 2011.
dc.identifier.doi10.1590/S0102-695X2011005000066
dc.identifier.fileS0102-695X2011000300008.pdf
dc.identifier.issn0102-695X
dc.identifier.lattes2518006820764120
dc.identifier.lattes4484083685251673
dc.identifier.lattes4702004904231248
dc.identifier.orcid0000-0002-1516-7765
dc.identifier.scieloS0102-695X2011000300008
dc.identifier.urihttp://hdl.handle.net/11449/26284
dc.identifier.wosWOS:000292919800008
dc.language.isoeng
dc.publisherSociedade Brasileira de Farmacognosia
dc.relation.ispartofRevista Brasileira de Farmacognosia
dc.relation.ispartofjcr1.596
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectMyrcia unifloraen
dc.subjectpedra-hume-caáen
dc.subjectHPLCen
dc.subjectmyricitrinen
dc.subjectstandardizationen
dc.titleDevelopment and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia unifloraen
dc.typeArtigo
dcterms.rightsHolderSoc Brasileira Farmacognosia
dspace.entity.typePublication
unesp.author.lattes2518006820764120[8]
unesp.author.lattes4484083685251673
unesp.author.lattes4702004904231248[10]
unesp.author.orcid0000-0002-1516-7765[10]
unesp.author.orcid0000-0001-8214-9957[8]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Orgânica - IQARpt

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Araraquara - IQAR - Instituto de Química