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Quantitative determination of cytotoxic friedo-nor-oleanane derivatives from five morphological types of Maytenus ilicifolia (Celastraceae) by reverse-phase high-performance liquid chromatography

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dc.contributor.authorBuffa, W.
dc.contributor.authorCorsino, J.
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorFurlan, Maysa [UNESP]
dc.contributor.authorPereira, AMS
dc.contributor.authorFranca, S. C.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUNAERP
dc.date.accessioned2014-05-20T15:26:53Z
dc.date.available2014-05-20T15:26:53Z
dc.date.issued2002-03-01
dc.description.abstractFive different morphological types of Maytenus ilicifolia of the same age and harvested under the same conditions showed distinct accumulations of some friedo-nor-oleananes. A rapid, sensitive and reliable reverse-phase HPLC method (employing an external standard) was used for the determination of the cytotoxic triterpenoids, 20alpha-hydroxymaytenin, 22beta-hydroxymaytenin, maytenin, celastrol and pristimerin in each of the five types. Well resolved peaks with good detection response and linearity in the range 1.0-100 mug/mL were obtained. Copyright (C) 2002 John Wiley Sons, Ltd.en
dc.description.affiliationUniv Estadual Paulista, Inst Quim, BR-14801970 Araraquara, SP, Brazil
dc.description.affiliationUNAERP, Dept Biotechnol, BR-14096380 Ribeirao Preto, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Inst Quim, BR-14801970 Araraquara, SP, Brazil
dc.format.extent75-78
dc.identifierhttp://dx.doi.org/10.1002/pca.626
dc.identifier.citationPhytochemical Analysis. W Sussex: John Wiley & Sons Ltd, v. 13, n. 2, p. 75-78, 2002.
dc.identifier.doi10.1002/pca.626
dc.identifier.issn0958-0344
dc.identifier.lattes4484083685251673
dc.identifier.lattes1308042794786872
dc.identifier.urihttp://hdl.handle.net/11449/36951
dc.identifier.wosWOS:000174650500003
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofPhytochemical Analysis
dc.relation.ispartofjcr2.337
dc.relation.ispartofsjr0,841
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.subjectreverse-phase high-performance liquid chromatographypt
dc.subjectquantitative determinationpt
dc.subjectfriedo-nor-oleanane derivativespt
dc.subjectroot barkpt
dc.subjectMaytenus ilicifoliapt
dc.subjectCelastraceaept
dc.subjectmorphological typespt
dc.titleQuantitative determination of cytotoxic friedo-nor-oleanane derivatives from five morphological types of Maytenus ilicifolia (Celastraceae) by reverse-phase high-performance liquid chromatographyen
dc.typeArtigopt
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell
dspace.entity.typePublication
relation.isOrgUnitOfPublicationbc74a1ce-4c4c-4dad-8378-83962d76c4fd
relation.isOrgUnitOfPublication.latestForDiscoverybc74a1ce-4c4c-4dad-8378-83962d76c4fd
unesp.author.lattes4484083685251673
unesp.author.lattes1308042794786872
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Orgânica - IQARpt

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