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Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil

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dc.contributor.authorKobayashi, Yuki
dc.contributor.authorOkuda, Hiromi
dc.contributor.authorNakamura, Kana
dc.contributor.authorSato, Go
dc.contributor.authorItou, Takuya
dc.contributor.authorCarvalho, Adolorata A. B. [UNESP]
dc.contributor.authorSilva, Marlon V.
dc.contributor.authorMota, Carla S.
dc.contributor.authorIto, Fumio H.
dc.contributor.authorSakai, Takeo
dc.contributor.institutionNihon Univ
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionJorge Vaitsmann Municipal Inst
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T15:23:00Z
dc.date.available2014-05-20T15:23:00Z
dc.date.issued2007-11-01
dc.description.abstractTo investigate the genetic characteristics of phosphoprotein (P) and matrix protein (M) genes of variable rabies virus (RV) prevalent in Brazil, the authors genetically characterized the P and M genes from 30 Brazilian RV field isolates. Phylogenetic analysis based on the P and M genes revealed the presence of six RV variants that consisted primarily of three insectivorous bats, the vampire bat, dog and fox in Brazil. Specific amino acid substitutions corresponding to these phylogenetic lineages were observed, with ASP(42) and GlU(62) in the P protein found to be characteristic of Brazilian chiroptera- and carnivora-related RVs, respectively. Amino acid sequence motifs predicted to associate with a viral function in the P and M proteins were conserved among Brazilian RV variants.en
dc.description.affiliationNihon Univ, Vet Res Ctr, Kanagawa 2528510, Japan
dc.description.affiliationUniv Estadual Paulista, Fac Agr & Vet Sci, BR-14884900 São Paulo, Brazil
dc.description.affiliationJorge Vaitsmann Municipal Inst, Rio de Janeiro, Brazil
dc.description.affiliationUniv São Paulo, Fac Vet Med & Zootechny, BR-05508000 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Agr & Vet Sci, BR-14884900 São Paulo, Brazil
dc.format.extent1145-1154
dc.identifierhttp://dx.doi.org/10.1292/jvms.69.1145
dc.identifier.citationJournal of Veterinary Medical Science. Tokyo: Japan Soc Vet Sci, v. 69, n. 11, p. 1145-1154, 2007.
dc.identifier.doi10.1292/jvms.69.1145
dc.identifier.fileWOS000251744200007.pdf
dc.identifier.issn0916-7250
dc.identifier.lattes4098511928890053
dc.identifier.lattes9477933792138174
dc.identifier.urihttp://hdl.handle.net/11449/33864
dc.identifier.wosWOS:000251744200007
dc.language.isoeng
dc.publisherJapan Soc Vet Sci
dc.relation.ispartofJournal of Veterinary Medical Science
dc.relation.ispartofjcr0.803
dc.relation.ispartofsjr0,459
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectBrazilpt
dc.subjectgenetic analysispt
dc.subjectmatrix proteinpt
dc.subjectphosphoproteinpt
dc.subjectrabies viruspt
dc.titleGenetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazilen
dc.typeArtigo
dcterms.licensehttps://www.jstage.jst.go.jp/pub/html/AY04S120_en.html
dcterms.rightsHolderJapan Soc Vet Sci
dspace.entity.typePublication
unesp.author.lattes4098511928890053
unesp.author.lattes9477933792138174[6]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Engenharia, Baurupt
unesp.departmentEngenharia Mecânica - FEBpt

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Bauru - FEB - Faculdade de Engenharia