Publicação: Optimized Diagnostic Assays Based on Redox Tagged Bioreceptive Interfaces
| dc.contributor.author | Bedatty Fernandes, Flavio C. [UNESP] | |
| dc.contributor.author | Patil, Amol V. | |
| dc.contributor.author | Bueno, Paulo R. [UNESP] | |
| dc.contributor.author | Davis, Jason J. | |
| dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
| dc.contributor.institution | University of Oxford | |
| dc.date.accessioned | 2018-12-11T16:59:42Z | |
| dc.date.available | 2018-12-11T16:59:42Z | |
| dc.date.issued | 2015-12-15 | |
| dc.description.abstract | Among the numerous label free electronic biomarker assay methodologies now available, impedance based electrochemical capacitance spectroscopy (ECS), based upon mapping the perturbations in interfacial charging of redox elements incorporated into a biologically receptive interface, has recently been shown to be a convenient and highly sensitive mode of transduction and one which, additionally, requires no predoping of analytical solution. We present, herein, a data acquisition and analysis methodology based on frequency resolved immittance function analysis. Ultimately, this enables both a maximization of assay sensitivity and a reduction in assay acquisition time by an order of magnitude. | en |
| dc.description.affiliation | Institute of Chemistry Physical Chemistry Department Nanobionics Group Univ. Estadual Paulista (São Paulo State University UNESP), CP 355 | |
| dc.description.affiliation | Department of Chemistry University of Oxford, South Parks Road | |
| dc.description.affiliationUnesp | Institute of Chemistry Physical Chemistry Department Nanobionics Group Univ. Estadual Paulista (São Paulo State University UNESP), CP 355 | |
| dc.format.extent | 12137-12144 | |
| dc.identifier | http://dx.doi.org/10.1021/acs.analchem.5b02976 | |
| dc.identifier.citation | Analytical Chemistry, v. 87, n. 24, p. 12137-12144, 2015. | |
| dc.identifier.doi | 10.1021/acs.analchem.5b02976 | |
| dc.identifier.issn | 1520-6882 | |
| dc.identifier.issn | 0003-2700 | |
| dc.identifier.scopus | 2-s2.0-84950107826 | |
| dc.identifier.uri | http://hdl.handle.net/11449/172319 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Analytical Chemistry | |
| dc.relation.ispartofsjr | 2,362 | |
| dc.relation.ispartofsjr | 2,362 | |
| dc.rights.accessRights | Acesso restrito | |
| dc.source | Scopus | |
| dc.title | Optimized Diagnostic Assays Based on Redox Tagged Bioreceptive Interfaces | en |
| dc.type | Artigo | |
| dspace.entity.type | Publication | |
| unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Química, Araraquara | pt |
| unesp.department | Físico-Química - IQAR | pt |