Triterpenes and saponins from Rudgea viburnioides
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American Chemical Society (ACS)
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Resumo
A novel triterpene; viburgenin (1), has been isolated from an extract of the ripe fruit rinds of Rudgea viburnioides, together with the known saponins, arjunglucoside I and trachelosperosides B-1 and E-l, and the triterpenes trachelosperogenin B (2) and arjungenin. Compound 2 was previously obtained as a product from enzymatic hydrolysis, and it is reported for the first time as a natural product. The structure of compound 1 was determined as 2α,3β,19α,23,24-pentahydroxyurs-12-ene by extensive use of 1D and 2D NMR spectroscopic methods. Compound 1 exhibited moderate antifungal activity against Cladosporium cladosporioides.
Descrição
Palavras-chave
miconazole , nystatin , saponin , trachelosperogenin b , triterpene , unclassified drug , viburgenin , antifungal activity , bioassay , brazil , cladosporium , drug isolation , fruit , hydrolysis , mass spectrometry , nonhuman , nuclear magnetic resonance spectroscopy , Antifungal Agents , Brazil , Chromatography, Thin Layer , Cladosporium , Magnetic Resonance Spectroscopy , Mass Spectrometry , Microbial Sensitivity Tests , Plants, Medicinal , Saponins , Spectrophotometry, Infrared , Spectrophotometry, Ultraviolet , Triterpenes , Cladosporium cladosporioides , Rudgea , Rudgea viburnioides
Idioma
Inglês
Citação
Journal of Natural Products, v. 61, n. 7, p. 936-938, 1998.
