Triterpenes and saponins from Rudgea viburnioides
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American Chemical Society (ACS)
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Resumo
A novel triterpene; viburgenin (1), has been isolated from an extract of the ripe fruit rinds of Rudgea viburnioides, together with the known saponins, arjunglucoside I and trachelosperosides B-1 and E-l, and the triterpenes trachelosperogenin B (2) and arjungenin. Compound 2 was previously obtained as a product from enzymatic hydrolysis, and it is reported for the first time as a natural product. The structure of compound 1 was determined as 2α,3β,19α,23,24-pentahydroxyurs-12-ene by extensive use of 1D and 2D NMR spectroscopic methods. Compound 1 exhibited moderate antifungal activity against Cladosporium cladosporioides.
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Palavras-chave
miconazole nystatin saponin trachelosperogenin b triterpene unclassified drug viburgenin antifungal activity bioassay brazil cladosporium drug isolation fruit hydrolysis mass spectrometry nonhuman nuclear magnetic resonance spectroscopy Antifungal Agents Brazil Chromatography, Thin Layer Cladosporium Magnetic Resonance Spectroscopy Mass Spectrometry Microbial Sensitivity Tests Plants, Medicinal Saponins Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Triterpenes Cladosporium cladosporioides Rudgea Rudgea viburnioides
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Inglês
Citação
Journal of Natural Products, v. 61, n. 7, p. 936-938, 1998.
