nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity
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Chemical examination of the leaves of Styrax ferrugineus yielded 5-[3'-(β-D-glucopyranosyloxy)propyl]-7-methoxy-2-(3',4'-dime-thoxyphenyl) benzofuran, along with the known nor-lignans 5-(3'-hydroxypropyl)-7-methoxy-2-(3',4'-methylenedioxyphenyl) benzofuran, 5-(3'-hydroxypropyl)-7-methoxy-2-(3',4'-dimethoxyphenyl)benzofuran, 5-[3'-(β-D-glucopyranosyloxy)propyl]-7-methoxy-2-(3', 4'-methylenedioxyphenyl)benzofuran and the lignan, dihydrodehydrodiconiferyl alcohol. All arylpropanoids isolated showed antibacterial and antifungal activities. The structures of the isolates were established by spectroscopic analysis. (C) 2000 Elsevier Science Ltd.
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Antibacterial activity Antifungal activity nor-Lignans Styracaceae Styrax ferrugineus 5 (3'' hydroxypropyl) 7 methoxy 2 (3',4' dimethoxyphenyl)benzofuran 5 (3'' hydroxypropyl) 7 methoxy 2 (3',4' methylenedioxyphenyl)benzofuran 5 [3'' (beta dextro glucopyranosyloxy)propyl] 7 methoxy 2 (3',4' dimethoxyphenyl)benzofuran 5 [3'' (beta dextro glucopyranosyloxy)propyl] 7 methoxy 2 (3',4' methylenedioxyphenyl)benzofuran Anti Infective Agents antifungal agent antiinfective agent dihydrodehydrodiconiferyl alcohol lignan lignan derivative unclassified drug angiosperm antibacterial activity antifungal activity antimicrobial activity Candida albicans Cladosporium Cladosporium sphaerospermum conformation drug isolation drug structure microbiological examination nonhuman nuclear magnetic resonance spectroscopy plant plant leaf Staphylococcus aureus structure analysis Angiosperms Anti-Bacterial Agents Anti-Infective Agents Antifungal Agents Lignans Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Molecular Conformation Plant Leaves Magnoliophyta
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Phytochemistry, v. 55, n. 6, p. 597-601, 2000.
