The Dual-Tasking Overload on Functional Mobility Is Related to Specific Cognitive Domains in Different Subtypes of Parkinson's Disease

Abstract

To investigate the role of different cognitive domains on the dual-tasking overload during functional mobility in Parkinson's disease subtypes. Methods: Eleven tremor-dominant and 15 akinetic-rigid participants performed the Timed Up-and-Go (TUG) test with and without a secondary task; executive function and attention were assessed. Results: Dual tasking increased TUG time in both groups (tremor-dominant: 6.38 ± 1.19 seconds and 7.79 ± 1.48 seconds; akinetic-rigid: 8.80 ± 3.09 seconds and 10.38 ± 3.77 seconds). Dual-tasking overload was correlated with attention in akinetic-rigid and mental inflexibility in tremor-dominant participants. Cognitive scores were similar between groups. Conclusion: Distinguished cognitive domains are involved with dual-tasking overload in Parkinson's disease subgroups.