Calcium-independent membrane damage by venom phospholipases A2
| dc.contributor.author | De Oliveira, A. H.C. | |
| dc.contributor.author | Aragão, E. A. | |
| dc.contributor.author | Sá, J. M. | |
| dc.contributor.author | Chioato, L. | |
| dc.contributor.author | Bugs-Bortoleto, R. [UNESP] | |
| dc.contributor.author | Ruller, R. | |
| dc.contributor.author | Ferreira, T. L. | |
| dc.contributor.author | Ward, R. J. | |
| dc.contributor.institution | Universidade de São Paulo (USP) | |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
| dc.date.accessioned | 2022-04-28T18:56:06Z | |
| dc.date.available | 2022-04-28T18:56:06Z | |
| dc.date.issued | 2009-01-01 | |
| dc.description.abstract | Many snake venom phospholipase A2s (vPLA2s) present biological effects that are independent of hydrolytic activity. Here we review the evidence for the calcium-independent membrane damaging activity of vPLA 2s, the possible relevance of this activity on their biological effects, and models for the mechanism of membrane permeabilization by these proteins. © 2009 Bentham Science Publishers Ltd. | en |
| dc.description.affiliation | Departamento de Química FFCLRP-USP Universidade de São Paulo | |
| dc.description.affiliation | Departamento de Bioquímica e Immunologia FMRP-USP Universidade de São Paulo | |
| dc.description.affiliation | Departamento de Física IBILICE-UNESP Universidade Estadual de São Paulo | |
| dc.description.affiliationUnesp | Departamento de Física IBILICE-UNESP Universidade Estadual de São Paulo | |
| dc.format.extent | 877-886 | |
| dc.identifier | http://dx.doi.org/10.2174/092986609788923392 | |
| dc.identifier.citation | Protein and Peptide Letters, v. 16, n. 8, p. 877-886, 2009. | |
| dc.identifier.doi | 10.2174/092986609788923392 | |
| dc.identifier.issn | 0929-8665 | |
| dc.identifier.scopus | 2-s2.0-68849106813 | |
| dc.identifier.uri | http://hdl.handle.net/11449/219518 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Protein and Peptide Letters | |
| dc.source | Scopus | |
| dc.subject | Membrane permeabilization | |
| dc.subject | Micelle nucleation | |
| dc.subject | Molecular mechanism | |
| dc.title | Calcium-independent membrane damage by venom phospholipases A2 | en |
| dc.type | Artigo | pt |
| dspace.entity.type | Publication | |
| unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto | pt |