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Flavonoids and lignans from Virola surinamensis twigs and their in vitro activity against Trypanosoma cruzi

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dc.contributor.authorLopes, N. P.
dc.contributor.authorChicaro, P.
dc.contributor.authorKato, M. J.
dc.contributor.authorAlbuquerque, S.
dc.contributor.authorYoshida, M.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:22:45Z
dc.date.available2014-05-20T15:22:45Z
dc.date.issued1998-10-01
dc.description.abstractDichloromethane extracts from twigs of Virola surinamensis (Myristicaceae) showed in vitro trypanosomicidal activity against trypomastigote form of Trypanosoma cruzi. The extract, fractionated by preparative circular chromatography and preparative high-performance liquid chromatography yielded two steroids, two lignans, five flavonoids, and one polyketide. Among the isolated compounds, the lignans presented the highest trypanosomicidal activity.en
dc.description.affiliationUniv São Paulo, Inst Quim, BR-05508900 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Fac Ciências Farmaceut Ribeirao Preto, BR-14049 Ribeirao Preto, Brazil
dc.description.affiliationUniv Estadual Paulista, Inst Quim, Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Inst Quim, Araraquara, SP, Brazil
dc.format.extent667-669
dc.identifierhttp://dx.doi.org/10.1055/s-2006-957548
dc.identifier.citationPlanta Medica. Stuttgart: Georg Thieme Verlag, v. 64, n. 7, p. 667-669, 1998.
dc.identifier.doi10.1055/s-2006-957548
dc.identifier.issn0032-0943
dc.identifier.urihttp://hdl.handle.net/11449/33681
dc.identifier.wosWOS:000076566400023
dc.language.isoeng
dc.publisherGeorg Thieme Verlag
dc.relation.ispartofPlanta Medica
dc.relation.ispartofjcr2.494
dc.relation.ispartofsjr0,581
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.titleFlavonoids and lignans from Virola surinamensis twigs and their in vitro activity against Trypanosoma cruzien
dc.typeArtigopt
dcterms.licensehttp://www.thieme.com//media/ita/pubid-1019644585.pdf
dcterms.rightsHolderGeorg Thieme Verlag
dspace.entity.typePublication
relation.isOrgUnitOfPublicationbc74a1ce-4c4c-4dad-8378-83962d76c4fd
relation.isOrgUnitOfPublication.latestForDiscoverybc74a1ce-4c4c-4dad-8378-83962d76c4fd
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt

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Araraquara - IQAR - Instituto de Química