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Tests to determine LC50 and discriminating doses for macrocyclic lactones against the cattle tick, Boophilus microplus

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dc.contributor.authorSabatini, G. A.
dc.contributor.authorKemp, D. H.
dc.contributor.authorHughes, S.
dc.contributor.authorNari, A.
dc.contributor.authorHansen, J.
dc.contributor.institutionCSIRO
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFAO
dc.date.accessioned2014-05-20T15:19:52Z
dc.date.available2014-05-20T15:19:52Z
dc.date.issued2001-02-05
dc.description.abstractLaboratory tests were carried out on larvae and adults of the cattle tick Boophilus microplus to determine the toxicity of macrocyclic lactone acaricides (MLs). Technical and commercial MLs were used in larval packet test (LPT), larval immersion test (LIT) and adult immersion test (AIT). Tn LIT and AIT the toxicity of MLs was much higher than for LPT. In the AIT, diluting the injectable formulation of MLs in water was as effective as dilution in ethanol + Triton X-100. LC50, LC99.9 and 95% confidence limits were determined so that a discriminating dose (DD) could be set for larval and adult tests in order to diagnose potential resistance to MLs in field samples of the tick. These DDs are for Australian strains of B. microplus and may not be suitable for other strains until further work is carried out.The value of these diagnostic tests can only be verified if or when resistance to MLs emerges in ticks. (C) 2001 Elsevier B.V. B.V. All rights reserved.en
dc.description.affiliationCSIRO, Long Pocket Labs, Indooroopilly, Qld 4068, Australia
dc.description.affiliationUniv Estadual Paulista, CPPAR, Jaboticabal, Brazil
dc.description.affiliationFAO, Anim Prod & Hlth Div, I-00100 Rome, Italy
dc.description.affiliationUnespUniv Estadual Paulista, CPPAR, Jaboticabal, Brazil
dc.format.extent53-62
dc.identifierhttp://dx.doi.org/10.1016/S0304-4017(00)00406-4
dc.identifier.citationVeterinary Parasitology. Amsterdam: Elsevier B.V., v. 95, n. 1, p. 53-62, 2001.
dc.identifier.doi10.1016/S0304-4017(00)00406-4
dc.identifier.issn0304-4017
dc.identifier.urihttp://hdl.handle.net/11449/31257
dc.identifier.wosWOS:000166569500006
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofVeterinary Parasitology
dc.relation.ispartofjcr2.422
dc.relation.ispartofsjr1,275
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectBoophilus micropluspt
dc.subjectmacrocyclic lactonespt
dc.subjectresistance testspt
dc.titleTests to determine LC50 and discriminating doses for macrocyclic lactones against the cattle tick, Boophilus microplusen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication

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