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BIOACTIVE AND OTHER PIPERIDINE ALKALOIDS FROM CASSIA-LEPTOPHYLLA

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dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorGunatilaka, AAL
dc.contributor.authorKingston, DGI
dc.contributor.institutionVIRGINIA POLYTECH INST & STATE UNIV
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:27:52Z
dc.date.available2014-05-20T15:27:52Z
dc.date.issued1995-05-22
dc.description.abstractFour new piperidine alkaloids, leptophyllin A (4), 3-acetylleptophyllin A (5), leptophyllin B (8), and (-)-spectaline (1), and 3 known piperidine alkaloids, (-)-spectalinine (2), canavaline (3), and iso-6-canavaline (7), were isolated by a bioassay-guided fractionation of a leaf extract of Cassia leptophylla. The alkaloids 1 - 3 were active in a mechanism-based DNA-modifying yeast assay and 2 was moderately active in Vero monkey and Chinese hamster ovary cell cytotoxicity assays.en
dc.description.affiliationVIRGINIA POLYTECH INST & STATE UNIV,DEPT CHEM,BLACKSBURG,VA 24061
dc.description.affiliationUNIV ESTADUAL PAULISTA,INST QUIM,BR-14800 ARARAQUARA,SP,BRAZIL
dc.description.affiliationUnespUNIV ESTADUAL PAULISTA,INST QUIM,BR-14800 ARARAQUARA,SP,BRAZIL
dc.format.extent5929-5934
dc.identifierhttp://dx.doi.org/10.1016/0040-4020(95)00254-6
dc.identifier.citationTetrahedron. Oxford: Pergamon-Elsevier B.V., v. 51, n. 21, p. 5929-5934, 1995.
dc.identifier.doi10.1016/0040-4020(95)00254-6
dc.identifier.issn0040-4020
dc.identifier.lattes4484083685251673
dc.identifier.urihttp://hdl.handle.net/11449/37782
dc.identifier.wosWOS:A1995QZ65600001
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofTetrahedron
dc.relation.ispartofjcr2.377
dc.relation.ispartofsjr0,800
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleBIOACTIVE AND OTHER PIPERIDINE ALKALOIDS FROM CASSIA-LEPTOPHYLLAen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.author.lattes4484083685251673
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Orgânica - IQARpt

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Araraquara - IQAR - Instituto de Química