Publicação: Calcium-Independent Membrane Damage by Venom Phospholipases A(2)
dc.contributor.author | de Oliveira, A. H. C. | |
dc.contributor.author | Aragao, E. A. | |
dc.contributor.author | Sa, J. M. | |
dc.contributor.author | Chioato, L. | |
dc.contributor.author | Bugs-Bortoleto, R. [UNESP] | |
dc.contributor.author | Ruller, R. | |
dc.contributor.author | Ferreira, T. L. | |
dc.contributor.author | Ward, R. J. | |
dc.contributor.institution | Universidade de São Paulo (USP) | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2014-05-20T15:30:20Z | |
dc.date.available | 2014-05-20T15:30:20Z | |
dc.date.issued | 2009-08-01 | |
dc.description.abstract | Many snake venom phospholipase A(2)s (vPLA(2)s) present biological effects that are independent of hydrolytic activity. Here we review the evidence for the calcium-independent membrane damaging activity of vPLA(2)s, the possible relevance of this activity on their biological effects, and models for the mechanism of membrane permeabilization by these proteins. | en |
dc.description.affiliation | Univ São Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Ribeirao Preto, SP, Brazil | |
dc.description.affiliation | Univ São Paulo, FMRP, Dept Bioquim & Immunol, BR-14040901 Ribeirao Preto, SP, Brazil | |
dc.description.affiliation | Univ Estadual São Paulo, UNESP, IBILICE, Dept Fis, São Paulo, Brazil | |
dc.description.affiliationUnesp | Univ Estadual São Paulo, UNESP, IBILICE, Dept Fis, São Paulo, Brazil | |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | |
dc.description.sponsorship | Fundação de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da USP (FAEPA) | |
dc.description.sponsorship | PRP-USP | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.format.extent | 877-886 | |
dc.identifier | http://eurekaselect.com/84727/article | |
dc.identifier.citation | Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 8, p. 877-886, 2009. | |
dc.identifier.issn | 0929-8665 | |
dc.identifier.uri | http://hdl.handle.net/11449/39745 | |
dc.identifier.wos | WOS:000268890600004 | |
dc.language.iso | eng | |
dc.publisher | Bentham Science Publ Ltd | |
dc.relation.ispartof | Protein and Peptide Letters | |
dc.relation.ispartofjcr | 1.039 | |
dc.relation.ispartofsjr | 0,429 | |
dc.rights.accessRights | Acesso restrito | pt |
dc.source | Web of Science | |
dc.subject | Membrane permeabilization | en |
dc.subject | molecular mechanism | en |
dc.subject | micelle nucleation | en |
dc.title | Calcium-Independent Membrane Damage by Venom Phospholipases A(2) | en |
dc.type | Artigo | pt |
dcterms.license | http://www.benthamscience.com/permission.php | |
dcterms.rightsHolder | Bentham Science Publ Ltd | |
dspace.entity.type | Publication | |
unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto | pt |
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