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Lipid peroxidation: the role or Ca2+ and protection by calcinine

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dc.contributor.authorPereira, R. S. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:18:06Z
dc.date.available2014-05-27T11:18:06Z
dc.date.issued1996-08-07
dc.description.abstractWhen calcinine (A-23187) (2 mu M), a known Ca2+ ionophore, is present, a significant protection is observed to a mitochondrial suspension undergoing lipid peroxidation by Fe2+-citrate complex. A-23187 can remove Ca2+, which seems to have an important role in the lipid peroxidation process, from its 'lesive sites' and consequently preventing the damage. This information has importance in terms of knowing the mechanisms and avoiding the damages of lipid peroxidation that occur in some pathological cases such as tumor promotion and hemochromatosis.en
dc.description.affiliationDepartment of Biochemistry Institute of Chemistry Universidade Estadual Paulista (UNESP), Araraquara, São Paulo
dc.description.affiliationDepartment of Biochemistry Institute of Chemistry Universidade Estadual Paulista (UNESP), C.P. 355, Araraquara, S.P. 14801-970
dc.description.affiliationUnespDepartment of Biochemistry Institute of Chemistry Universidade Estadual Paulista (UNESP), Araraquara, São Paulo
dc.description.affiliationUnespDepartment of Biochemistry Institute of Chemistry Universidade Estadual Paulista (UNESP), C.P. 355, Araraquara, S.P. 14801-970
dc.format.extent23-26
dc.identifierhttp://dx.doi.org/10.1007/BF03190274
dc.identifier.citationEuropean Journal of Drug Metabolism and Pharmacokinetics, v. 21, n. 1, p. 23-26, 1996.
dc.identifier.doi10.1007/BF03190274
dc.identifier.issn0378-7966
dc.identifier.scopus2-s2.0-0030035915
dc.identifier.urihttp://hdl.handle.net/11449/130470
dc.identifier.wosWOS:A1996UY20800005
dc.language.isoeng
dc.publisherMedecine Et Hygiene
dc.relation.ispartofEuropean Journal of Drug Metabolism and Pharmacokinetics
dc.relation.ispartofjcr1.362
dc.relation.ispartofsjr0,338
dc.rights.accessRightsAcesso restritopt
dc.sourceScopus
dc.subjectA-23187
dc.subjectCa2+
dc.subjectLipid peroxidation
dc.subjectMitochondria
dc.subjectCalcimycin
dc.subjectCalcium ion
dc.subjectFerric citrate
dc.subjectAnimal tissue
dc.subjectControlled study
dc.subjectHemochromatosis
dc.subjectLipid peroxidation
dc.subjectMitochondrion
dc.subjectNonhuman
dc.subjectRat
dc.subjectTumor promotion
dc.subjectAnimals
dc.subjectCalcimycin
dc.subjectCalcium
dc.subjectIonophores
dc.subjectLipid Peroxidation
dc.subjectMembrane Potentials
dc.subjectMitochondria, Liver
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectReactive Oxygen Species
dc.titleLipid peroxidation: the role or Ca2+ and protection by calcinineen
dc.typeArtigopt
dcterms.licensehttp://www.springer.com/open+access/authors+rights
dcterms.rightsHolderMedecine Et Hygiene
dspace.entity.typePublication
relation.isOrgUnitOfPublicationbc74a1ce-4c4c-4dad-8378-83962d76c4fd
relation.isOrgUnitOfPublication.latestForDiscoverybc74a1ce-4c4c-4dad-8378-83962d76c4fd
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentBioquímica e Tecnologia - IQpt

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Araraquara - IQAR - Instituto de Química