Publicação: The alpha 7, alpha 4 beta 2 and alpha 3 beta 4 Nicotinic Acetylcholine Receptors: Characteristics, Role in Pathogenic Processes and Bioactive Compounds
| dc.contributor.author | Batista, V. S. [UNESP] | |
| dc.contributor.author | Nascimento-Junior, N. R. [UNESP] | |
| dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
| dc.date.accessioned | 2018-11-26T17:41:40Z | |
| dc.date.available | 2018-11-26T17:41:40Z | |
| dc.date.issued | 2016-01-01 | |
| dc.description.abstract | Neuronal nicotinic acetylcholine receptors (nAChRs) are potential targets for the treatement of several central nervous system disorders, including Alzheimer's disease, Parkinson's disease and schzophrenia. On this review will be discussed the main characteristics of the nAChRs, more specifically of the alpha 7, alpha 4 beta 2 and alpha 3 beta 4 subtypes, examples of bioactive compounds that act on these receptors and structureactivity relationships of some compounds on their respective target receptors. | en |
| dc.description.affiliation | Univ Estadual Paulista, Inst Quim, Dept Quim Organ, Lab Quim Med Sintese Organ & Modelagem Mol LaQMed, Campus Araraquara, BR-14800060 Araraquara, SP, Brazil | |
| dc.description.affiliationUnesp | Univ Estadual Paulista, Inst Quim, Dept Quim Organ, Lab Quim Med Sintese Organ & Modelagem Mol LaQMed, Campus Araraquara, BR-14800060 Araraquara, SP, Brazil | |
| dc.format.extent | 1721-1739 | |
| dc.identifier | http://dx.doi.org/10.21577/1984-6835.20160114 | |
| dc.identifier.citation | Revista Virtual De Quimica. Niteroi: Brazilian Chemical Soc, v. 8, n. 5, p. 1721-1739, 2016. | |
| dc.identifier.doi | 10.21577/1984-6835.20160114 | |
| dc.identifier.issn | 1984-6835 | |
| dc.identifier.uri | http://hdl.handle.net/11449/163356 | |
| dc.identifier.wos | WOS:000412121700026 | |
| dc.language.iso | por | |
| dc.publisher | Brazilian Chemical Soc | |
| dc.relation.ispartof | Revista Virtual De Quimica | |
| dc.rights.accessRights | Acesso restrito | |
| dc.source | Web of Science | |
| dc.subject | Medicinal chemistry | |
| dc.subject | nicotinic acetylcholine receptors | |
| dc.subject | bioactive compounds | |
| dc.subject | structure-activity relationship | |
| dc.title | The alpha 7, alpha 4 beta 2 and alpha 3 beta 4 Nicotinic Acetylcholine Receptors: Characteristics, Role in Pathogenic Processes and Bioactive Compounds | en |
| dc.type | Artigo | |
| dcterms.rightsHolder | Brazilian Chemical Soc | |
| dspace.entity.type | Publication | |
| unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Química, Araraquara | pt |
| unesp.department | Química Orgânica - IQAR | pt |