Communiols E-H: New polyketide metabolites from the coprophilous fungus Podospora communis
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American Chemical Society (ACS)
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Resumo
Communiols E-H (1-4), four new polyketide-derived natural products containing furanocyclopentane, furanocyclopentene, cyclopentene, or γ-lactone moieties, have been isolated from two geographically distinct isolates of the coprophilous fungus Podospora communis. The structures of these compounds were determined by analysis of NMR and MS data. © 2005 American Chemical Society and American Society of Pharmacognosy.
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cyclopentane derivative , furan derivative , lactone , antifungal agent , antiinfective agent , communiol A , communiol B , communiol C , communiol D , communiol E , communiol F , communiol G , communiol H , cyclopentene derivative , furanocyclopentane derivative , furanocyclopentene derivative , gamma lactone derivative , natural product , polyketide , unclassified drug , chemical structure , chemistry , Ecuador , isolation and purification , mass spectrometry , nuclear magnetic resonance , Podospora , United States , antibacterial activity , antifungal activity , Bacillus subtilis , Candida albicans , carbon nuclear magnetic resonance , drug isolation , drug structure , fungus culture , fungus isolation , nonhuman , nuclear magnetic resonance spectroscopy , nuclear Overhauser effect , Podospora communis , proton nuclear magnetic resonance , Staphylococcus aureus , stereochemistry , structure analysis , California , Cyclopentanes , Furans , Lactones , Mass Spectrometry , Molecular Structure , Nuclear Magnetic Resonance, Biomolecular , Coprophilous , Fungi
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Inglês
Citação
Journal of Natural Products, v. 68, n. 3, p. 435-438, 2005.
