Evaluation of different media for the production of cephalosporins by Streptomyces clavuligerus ATCC 27064
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Brazilian Archives of Biology and Technology
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The aim of this work was to compare the composition of a complex and soluble culture medium to eight other media described in the literature through the batch cultivation in a conventional bench-scale bioreactor for the production of cephamycin C by a wild strain of Streptomyces clavuligerus. The proposed medium resulted in an antibiotic production 1.5 to 7.5 times higher than the other culture media.
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Brazilian Archives of Biology and Technology. Brazilian Archives of Biology and Technology, v. 55, n. 6, p. 819-825, 2012.
