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Flavonoids and a naphthopyranone from Eriocaulon ligulatum and their mutagenic activity

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dc.contributor.authorda Silva, Marcelo Aparecido [UNESP]
dc.contributor.authorSiqueira Oliveira, Ana Paula [UNESP]
dc.contributor.authorSannomiya, Miriam [UNESP]
dc.contributor.authorSano, Paulo Takeo
dc.contributor.authorVaranda, Eliana Aparecida [UNESP]
dc.contributor.authorVilegas, Wagner [UNESP]
dc.contributor.authorSantos, Lourdes Campaner dos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:24:29Z
dc.date.available2014-05-20T13:24:29Z
dc.date.issued2007-11-01
dc.description.abstractA new acylated flavonoid, 6,4'-dimethoxyquereetin-3-O-beta-D-6 ''[3,4,5-trihydroxy (E)-cinnamoyl]glucopyranoside, and a naphthopyranone dimer, named eriocauline, together with 2 other known flavonoids, 6-methoxyapigenin-7-O-beta-D-glucopyranoside and 6-methoxyapigenin-7-O-beta-D-allopyranoside, have been isolated from the capitulae of Eriocaulon ligulatum. The compounds were identified using spectroscopic methods (HR-ESI-MS, and 1-D and 2-D NMR). The methanol extract exhibited mutagenic activity in the Salmonella/microsome assay, in strains TA100, TA97a and TA102 and for dichloromethane extract tested in strain TA98.en
dc.description.affiliationUniv Estadual Paulista, Inst Quim Araraquara, Dept Organ Chem, BR-14801970 São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Ciências Farmaceut Araraquara, Dept Biol, BR-14801902 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Inst Biociencias, Dept Bot, BR-05422097 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Inst Quim Araraquara, Dept Organ Chem, BR-14801970 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Ciências Farmaceut Araraquara, Dept Biol, BR-14801902 São Paulo, Brazil
dc.format.extent1635-1639
dc.identifierhttp://dx.doi.org/10.1248/cpb.55.1635
dc.identifier.citationChemical & Pharmaceutical Bulletin. Tokyo: Pharmaceutical Soc Japan, v. 55, n. 11, p. 1635-1639, 2007.
dc.identifier.doi10.1248/cpb.55.1635
dc.identifier.fileWOS000251592600018.pdf
dc.identifier.issn0009-2363
dc.identifier.lattes3538253640602977
dc.identifier.orcid0000-0003-3032-2556
dc.identifier.urihttp://hdl.handle.net/11449/7604
dc.identifier.wosWOS:000251592600018
dc.language.isoeng
dc.publisherPharmaceutical Soc Japan
dc.relation.ispartofChemical & Pharmaceutical Bulletin
dc.relation.ispartofjcr1.258
dc.relation.ispartofsjr0,364
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectEriocaulon ligulatumpt
dc.subjectEriocaulaceaept
dc.subjectnaphthopyranonept
dc.subjectflavonoidpt
dc.subjectAmes testpt
dc.subjecthigh speed counter-current chromatographypt
dc.titleFlavonoids and a naphthopyranone from Eriocaulon ligulatum and their mutagenic activityen
dc.typeArtigo
dcterms.licensehttp://bpb.pharm.or.jp/document/transfer.pdf
dcterms.rightsHolderPharmaceutical Soc Japan
dspace.entity.typePublication
unesp.author.lattes3538253640602977
unesp.author.orcid0000-0003-3032-2556[6]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Orgânica - IQARpt

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Araraquara - IQAR - Instituto de Química