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Antifungal constituents from roots of Virola surinamensis

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dc.contributor.authorLopes, N. P.
dc.contributor.authorKato, M. J.
dc.contributor.authorYoshida, M.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:26:08Z
dc.date.available2014-05-20T15:26:08Z
dc.date.issued1999-05-01
dc.description.abstractChromatographic fractionation of the dichloromethane extract from roots of Virola surinamensis yielded two new natural products, 3-epi-juruenolide C and 2'-hydroxy-7,4'-dimethoxyisoflavone, as well as various known steroids, lignans, isoflavones, flavonoids and diarylpropanes. of these, alpha,2'-dihydroxy-4,3'-dimethoxydihydrochal biochanin A and 2'-hydroxy-7,4'-dimethoxyisoflavone displayed antifungal activity against Cladosporium cladosporioides at a minimum amount of 5 mu g, whereas 7-hydroxyflavanone and 7-hydroxy-4'-methoxyisoflavone exhibited an antifungal activity 10-fold higher than the positive control Nystatin. (C) 1999 Elsevier B.V. Ltd. All rights reserved.en
dc.description.affiliationUniv São Paulo, Inst Quim, BR-05599970 São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Inst Quim, BR-14800900 Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Inst Quim, BR-14800900 Araraquara, SP, Brazil
dc.format.extent29-33
dc.identifierhttp://dx.doi.org/10.1016/S0031-9422(98)00709-2
dc.identifier.citationPhytochemistry. Oxford: Pergamon-Elsevier B.V., v. 51, n. 1, p. 29-33, 1999.
dc.identifier.doi10.1016/S0031-9422(98)00709-2
dc.identifier.issn0031-9422
dc.identifier.urihttp://hdl.handle.net/11449/36348
dc.identifier.wosWOS:000080384200006
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofPhytochemistry
dc.relation.ispartofjcr3.186
dc.relation.ispartofsjr1,048
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.subjectVirola surinamensispt
dc.subjectMyristicaceaept
dc.subjectflavonoidspt
dc.subjectlignanspt
dc.subjectgamma-lactonespt
dc.subjectantifungal activitypt
dc.titleAntifungal constituents from roots of Virola surinamensisen
dc.typeArtigopt
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.author.orcid0000-0002-3315-2129[2]
unesp.author.orcid0000-0002-8159-3658[1]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt

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Araraquara - IQAR - Instituto de Química