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A new neolignan and antioxidant phenols from Nectandra grandiflora

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dc.contributor.authorRibeiro, Alan B. [UNESP]
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorYoshida, Massayoshi
dc.contributor.authorSantos, Leonardo S.
dc.contributor.authorEberlin, Marcos N.
dc.contributor.authorSilva, Dulce Helena Siqueira [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionInstituto de Pesquisas da Amazônia
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.date.accessioned2014-05-27T11:21:19Z
dc.date.available2014-05-27T11:21:19Z
dc.date.issued2005-05-01
dc.description.abstractThe EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards β-carotene in a TLC assay. The bioassay-guided fractionation led to the isolation of protocatechuic acid and two flavonol glycosides: afzelin and quercetrin, which showed free radical scavenging activity towards DPPH (ΔA 32, 16 and 73% at 50 μmol L-1) and were compared to commercial antioxidants rutin (81% at 50 μmol L-1) and BHT (9% at 50 μmol L-1), used as standard compounds. Additionally, three inactive neolignans, including the new bicycle[3.2.1]octane neolignan 2′-oxo-piperol B were obtained and characterized by spectrometric methods. ©2005 Sociedade Brasileira de Química.en
dc.description.affiliationInstituto de Química Universidade Estadual Paulista, CP 355, 14801-900 Araraquara - SP
dc.description.affiliationInstituto de Química Universidade de São Paulo, CP 26077, 05513-970 São Paulo - SP
dc.description.affiliationInstituto de Pesquisas da Amazônia, CP 476, 69083-000 Manaus - AM
dc.description.affiliationInstituto de Química Universidade Estadual de Campinas, CP 6154, 13084-971 Campinas - SP
dc.description.affiliationUnespInstituto de Química Universidade Estadual Paulista, CP 355, 14801-900 Araraquara - SP
dc.format.extent526-530
dc.identifierhttp://dx.doi.org/10.1590/S0103-50532005000400005
dc.identifier.citationJournal of the Brazilian Chemical Society, v. 16, n. 3 B, p. 526-530, 2005.
dc.identifier.doi10.1590/S0103-50532005000400005
dc.identifier.file2-s2.0-23744439433.pdf
dc.identifier.issn0103-5053
dc.identifier.lattes4484083685251673
dc.identifier.lattes4702004904231248
dc.identifier.orcid0000-0002-1516-7765
dc.identifier.scieloS0103-50532005000400005
dc.identifier.scopus2-s2.0-23744439433
dc.identifier.urihttp://hdl.handle.net/11449/68217
dc.identifier.wosWOS:000230754800005
dc.language.isoeng
dc.relation.ispartofJournal of the Brazilian Chemical Society
dc.relation.ispartofjcr1.444
dc.relation.ispartofsjr0,357
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAntioxidant
dc.subjectFlavonoid
dc.subjectLauraceae
dc.subjectNectandra grandiflora
dc.subjectNeolignan
dc.subjectRadical scavenging activity
dc.titleA new neolignan and antioxidant phenols from Nectandra grandifloraen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/jbchs/iaboutj.htm
dspace.entity.typePublication
unesp.author.lattes4484083685251673
unesp.author.lattes4702004904231248[6]
unesp.author.orcid0000-0002-1516-7765[6]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Orgânica - IQARpt

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