Pythium insidiosum: relato do primeiro caso de infecção humana no Brasil
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Data
2006-10-01
Autores
Marques, Silvio Alencar [UNESP]
Bagagli, Eduardo [UNESP]
Bosco, Sandra M. G. [UNESP]
Camargo, Rosangela M. P. [UNESP]
Marques, Mariângela Esther Alencar [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Sociedade Brasileira de Dermatologia
Resumo
A pitiose é causada por microorganismo aquático, fungo-símile, o Pythium insidiosum, patógeno de homens e animais. Observou-se um paciente com úlcera fagedênica no membro inferior, com exame anatomopatológico sugestivo de zigomicose, pouco sensível à terapêutica antifúngica, obtendo-se cura por meio de ampla exérese. A comprovação etiológica resultou de métodos moleculares, com amplificação e seqüenciamento de DNA de organismo isolado em ágar Sabouraud, observando-se 100% de analogia com seqüências de P. insidiosum depositadas no GenBank.
Pythiosis is caused by an aquatic fungus-like organism, Pythium insidiosum, pathogenic to men and animals. A patient with a phagedenic ulcer on the leg is reported. Histopathological examination was suggestive of zygomycosis, response to antifungal drugs was poor and cure was obtained by means of wide surgical excision. Etiologic diagnosis was confirmed by molecular amplification and DNA sequencing of colonies isolated in Sabouraud agar. After BLAST analysis, the sequence showed 100% identity with those of P. insidiosum deposited on the GenBank.
Pythiosis is caused by an aquatic fungus-like organism, Pythium insidiosum, pathogenic to men and animals. A patient with a phagedenic ulcer on the leg is reported. Histopathological examination was suggestive of zygomycosis, response to antifungal drugs was poor and cure was obtained by means of wide surgical excision. Etiologic diagnosis was confirmed by molecular amplification and DNA sequencing of colonies isolated in Sabouraud agar. After BLAST analysis, the sequence showed 100% identity with those of P. insidiosum deposited on the GenBank.
Descrição
Palavras-chave
Brasil, Humanos, Pythium, Úlcera cutânea, Brazil, Humans, Pythium, Skin ulcer
Como citar
Anais Brasileiros de Dermatologia. Sociedade Brasileira de Dermatologia, v. 81, n. 5, p. 483-485, 2006.