Show simple item record

dc.contributor.authorBrito, Graziella Nuernberg Back [UNESP]
dc.contributor.authorInocêncio, Aline Cássia [UNESP]
dc.contributor.authorQuerido, Sílvia Maria Rodrigues [UNESP]
dc.contributor.authorJorge, Antonio Olavo Cardoso [UNESP]
dc.contributor.authorKoga-ito, Cristiane Yumi [UNESP]
dc.date.accessioned2021-07-14T10:50:29Z
dc.date.available2021-07-14T10:50:29Z
dc.date.issued2011-02
dc.identifierhttp://dx.doi.org/10.1590/S1806-83242011005000001
dc.identifier.citationBrazilian Oral Research. São Paulo, SP, Brazil: Sociedade Brasileira de Pesquisa Odontológica - SBPqO, v. 25, n. 1, p. 28-33, 2011.
dc.identifier.issn1806-8324
dc.identifier.issn1807-3107
dc.identifier.urihttp://hdl.handle.net/11449/213132
dc.description.abstractOropharyngeal candidiasis is the most common fungal infection among HIV-positive patients. This condition can be treated with either systemic or topical antifungal agents; treatments are usually indicated empirically on the basis of clinical data. The knowledge of in vitro antifungal susceptibility is important to determine correct therapeutic guides for the treatment of fungal infections. Therefore, the objective of this study was to determine the antifungal susceptibility profile of oral Candida isolates from HIV-positive patients and control individuals. Amphotericin B, fluconazole, flucytosine, nystatin and ketoconazole were tested according to the methodology of microdilution proposed by the Clinical and Laboratory Standards Institute (CLSI); results were recorded in values of minimal inhibitory concentration (MIC). A total of 71 Candida isolates from HIV-positive patients were examined with the following species represented: C. albicans (59), C. tropicalis (9), C. glabrata (1), C. guilliermondii (1) and C. krusei (1). A total of 15 Candida isolates were evaluated from control individuals comprised of 11 C. albicans and 4 C. tropicalis samples. Our results demonstrated that the tested antifungal agents showed good activity for most isolates from both groups; however, variability in MIC values among isolates was observed.en
dc.format.extent28-33
dc.language.isoeng
dc.publisherSociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.relation.ispartofBrazilian Oral Research
dc.sourceSciELO
dc.subjectHIVen
dc.subjectAntifungal Agentsen
dc.subjectCandidaen
dc.titleIn vitro antifungal susceptibility of Candida spp. oral isolates from HIV-positive patients and control individualsen
dc.typeArtigo
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.affiliationUniversidade Estadual Paulista, São José dos Campos Dental School
dc.description.affiliationUnespUniversidade Estadual Paulista, São José dos Campos Dental School
dc.identifier.doi10.1590/S1806-83242011005000001
dc.identifier.scieloS1806-83242011000100006
dc.rights.accessRightsAcesso aberto
dc.identifier.fileS1806-83242011000100006.pdf
dc.identifier.lattes6543563161403421
dc.identifier.orcid0000-0002-2416-2173
unesp.author.lattes6543563161403421[5]
unesp.author.orcid0000-0002-2416-2173[5]
Localize o texto completo

Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record