O uso de animais em pesquisa: dor, estresse e eutanásia estão relacionados à publicação de resultados?
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Data
2023-01-25
Autores
Borges, Teubislete Ferreira
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Editor
Universidade Estadual Paulista (Unesp)
Resumo
Esse trabalho científico teve como objetivo quantificar o percentual de publicações de projetos com o envolvimento de animais, aprovados pela Comissão de Ética no Uso de Animais (CEUA) da Faculdade de Medicina Veterinária e Zootecnia (FMVZ) da UNESP do campus de Botucatu, entre 2000 e 2009. Ademais, também foi objetivo dessa pesquisa avaliar a existência de associação entre a submissão de animais a dor, estresse e eutanásia e a publicação dos trabalhos e contabilizar o número de animais usados nessas pesquisas. Para isso, todos os protocolos presentes na CEUA com entrada nesse intervalo de tempo foram acessados e optou-se por excluir desta pesquisa aqueles que não apresentassem o número de animais utilizados. Por esse motivo, do total de 1.334 projetos com envolvimento de animais, registrou-se os dados de 632 pesquisas, proporcionando um intervalo de confiança de 99% e uma margem de erro de 3,75%. Posteriormente, esses dados foram confrontados com as informações presentes nos currículos Lattes dos orientadores e orientados com a finalidade de se encontrar a informação das publicações dos artigos científicos das pesquisas. Em seguida foram enviados três e-mails para os orientadores e dois e-mails para os orientados cujas publicações não foram encontradas nos currículos Lattes, perguntando-lhes se publicaram o artigo científico completo das pesquisas e os dados dessas publicações para que pudéssemos confirmar o fato. Em conformidade com a resposta dos pesquisadores, os trabalhos foram separados em três grupos: pesquisas publicadas, pesquisas não publicadas e não se sabe. Averiguou-se que 65,3% das pesquisas foram publicadas; 24% não o foram e não se sabe sobre a publicação de 10,7% dos projetos. 31.521 animais foram utilizados em pesquisas não publicadas, destes 23.443 foram submetidos à eutanásia, 4.026 à estresse e 882 à dor. Logo, os resultados desta pesquisa mostram que um elevado número de animais passou por sofrimento desnecessariamente no desenvolvimento de pesquisas, devido à ausência de publicação das informações.
This research is aimed to quantify the percentage of paper publications of studies involving animals, approved by the Animal Ethics Committee of the School of Veterinary Medicine and Animal Science at São Paulo State University (UNESP), Botucatu, Brazil, from 2000 to 2009. Furthermore, this work aimed to evaluate if there is any association between the animal’s experience of pain, stress, and euthanasia. Also, to quantify the number of animals used submitted to pain, stress, and euthanasia of this published and unpublished research. According to the purpose, all protocols of the Animal Use Ethics Committee were accessed, and we decided to exclude from this work all protocols without the number of animals. For this reason, out of 1,334 protocols involving animals, data from 632 research were recorded which provided us a confidence interval of 99% and a margin of error of 3,75%. Subsequently, these data were compared with the present information in the researchers’ Lattes curricula to find paper publication. Then, three e-mails were sent to supervisors and two e-mails to pupils whose publications were not found in the researches Lattes curricula, questioning them if they had published the scientific work. In accordance with the researcher’s response, the projects were separated into three groups: published research, unpublished research, and unknown. It was found that 65.3% of research was published, 24% was not published and 10.7% of these studies are unknown. 31,521 animals were used in unpublished research, of which 23,443 were euthanized, 4,026 were submitted to stress, and 882 to painful procedures. In conclusion, our research showed a high number of animals were submitted unnecessarily to suffering in the development of research, due to lack of paper publication
This research is aimed to quantify the percentage of paper publications of studies involving animals, approved by the Animal Ethics Committee of the School of Veterinary Medicine and Animal Science at São Paulo State University (UNESP), Botucatu, Brazil, from 2000 to 2009. Furthermore, this work aimed to evaluate if there is any association between the animal’s experience of pain, stress, and euthanasia. Also, to quantify the number of animals used submitted to pain, stress, and euthanasia of this published and unpublished research. According to the purpose, all protocols of the Animal Use Ethics Committee were accessed, and we decided to exclude from this work all protocols without the number of animals. For this reason, out of 1,334 protocols involving animals, data from 632 research were recorded which provided us a confidence interval of 99% and a margin of error of 3,75%. Subsequently, these data were compared with the present information in the researchers’ Lattes curricula to find paper publication. Then, three e-mails were sent to supervisors and two e-mails to pupils whose publications were not found in the researches Lattes curricula, questioning them if they had published the scientific work. In accordance with the researcher’s response, the projects were separated into three groups: published research, unpublished research, and unknown. It was found that 65.3% of research was published, 24% was not published and 10.7% of these studies are unknown. 31,521 animals were used in unpublished research, of which 23,443 were euthanized, 4,026 were submitted to stress, and 882 to painful procedures. In conclusion, our research showed a high number of animals were submitted unnecessarily to suffering in the development of research, due to lack of paper publication
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Palavras-chave
Bioética, Bem-estar animal, Publicação, Direito dos animais