A novel PCR-RFLP assay for the detection of the single nucleotide polymorphism at position+1440 in the human CXCR2 gene

Resumo

We designed a novel PCR-RFLP assay to genotype for the CXCR2 +1440 (G/A) single nucleotide polymorphism, which provides a simple, low-cost, practical, and reproducible method. Allele frequencies in healthy Brazilian individuals were found to be 0.65% for allele A and 0.35% for allele G.

Descrição

Palavras-chave

PCR-RFLP, polymorphism, CXCR2, human

Como citar

Biochemical Genetics. New York: Springer/plenum Publishers, v. 45, n. 9-10, p. 737-741, 2007.