Determination of the sodium monofluoroacetate in serum by gas chromatography
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Data
2001-09-01
Autores
Demarchi, ACCO
Menezes, Manoel Lima de [UNESP]
Mercadante, A.
Vassillief, I
Título da Revista
ISSN da Revista
Título de Volume
Editor
Vieweg
Resumo
Sodium monofluoroacetate (NAFAc) has been widely used for vertebrate pest control, such as rabbits in Australia. However NAFAc is extremely toxic to all vertebrates and its use is restricted. Although this compound is stringently restricted, the occurrence of accidental and homicidal poisoning is no ever-present possibility.The method developed in this work shows the applicability of SPE with alumina cartridges for the extraction of NAFAc from serum samples. The method is efficient with recoveries of at least 96.8% from spiked serum. The samples were subsequently derivatized with dicyclohexylcabodiimide (DCC), using 2,4-dichloroaniline (DCA), to make the product volatile for GC analysis.
Descrição
Palavras-chave
gas chromatography, sodium monofluoroacetate, rodents, alumina
Como citar
Chromatographia. Wiesbaden: Vieweg, v. 54, n. 5-6, p. 402-404, 2001.