Clerodane diterpenes from leaves of Casearia sylvestris swartz
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Ethanolic extracts of the leaves of Casearia sylvestris yielded a novel clerodane diterpene, 15-hydroxy-3-cleroden-2-one, together with the known diterpenes (-)-hardwickiic acid, reported for the first time from this species, and casearins B and G, previously isolated from C. sylvestris. The structures of all four compounds were determined by spectrometric analysis. The new clerodane diterpene and (-)-hardwickiic acid contain structural features that are completely different from the highly oxygenated casearins and casearvestrins isolated from C. sylvestris.
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15-hydroxy-3-cleroden-2-one, Casearia sylvestris, Clerodane diterpenes
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Inglês
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Quimica Nova, v. 30, n. 5, p. 1100-1103, 2007.
