EFEITOS DA DEXAMETASONA 21 FOSFATO SOBRE AS GLANDULAS SALIVARES DE RATOS. ESTUDO HISTOQUIMICO
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1974-12-01
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Melhado, R. M.
Martinelli, C.
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The parotid, submandibular and sublingual glands of 12 male rats injected with dexamethasone 21 phosphate (0.20 mg per kg body weight) were removed and studied. Identical procedures were used in 12 male rats injected with 0.2 ml of distilled water (control group). All glands were stained by hematoxylin and eosin, Masson, periodic acid Schiff, chromic acid Schiff, Hale's colloidal iron, Alcian blue (pH 1.0 and 2.5), ninhydrin Schiff, ferric ferricyanide and gallocyanin chrome alum. Ribonuclease, testicular hyaluronidase, α amylase and blockade by acid hydrolysis were used. Dexamethasone caused: increased glycogen in submandibular (striated and granular) ducts and sublingual striated ducts; increased sulfhydril groups and RNA in parotid acini; increased amino groups in submandibular and parotid glands; increased sialic acid in sublingual glands (acini and crescent formations) and submandibular acini. (43 references).
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REV.FAC.ODONTOL.ARACATUBA, v. 3, n. 1, p. 87-99, 1974.