Immunophenotyping of thymic lymphoma in a Nelore cow

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dc.contributor.authorSampaio, Paulo H. [UNESP]
dc.contributor.authorFidelis Jr., Otávio L. [UNESP]
dc.contributor.authorde Queiroz, Daniela J. [UNESP]
dc.contributor.authorSoares, Luciana M.C. [UNESP]
dc.contributor.authorMoreira, Pamela R.R. [UNESP]
dc.contributor.authorVasconcelos, Rosemeri O. [UNESP]
dc.contributor.authorMarques, Luiz C. [UNESP]
dc.contributor.authorAlessi, Antonio C. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:26:52Z
dc.date.available2014-05-27T11:26:52Z
dc.date.issued2012-07-01
dc.description.abstractThymic lymphoma is a malignant lymphoid neoplasm that affects several species, including cattle. This type of neoplasia can lead to death due to malignant cell infiltration in different organs. The classification of this neoplasm may predict prognosis and response to treatment. Immunophenotyping is one of the ways to perform this classification. There are reports about the performance of immunohistochemistry (IHC) to classify thymic lymphoma only in taurine cattle, therefore the aim of this report is to describe the immunophenotype of a thymic lymphoma in a Nelore cow. Immunostaining was performed with monoclonal antibodies (CD79, CD4 and CD8). The tumor cells showed positive staining only for CD8 T lymphocytes, coinciding with the disease progression, since the T lymphoma type is more aggressive.en
dc.description.affiliationFCAV - Unesp/Jaboticabal
dc.description.affiliationUnespFCAV - Unesp/Jaboticabal
dc.format.extent94-98
dc.identifierhttp://www.abpv.vet.br/upload/documentos/DOWNLOAD-FULL-ARTICLE-21-20881_2012_8_18_27_4.pdf
dc.identifier.citationBrazilian Journal of Veterinary Pathology, v. 5, n. 2, p. 94-98, 2012.
dc.identifier.issn1983-0246
dc.identifier.scopus2-s2.0-84864846862
dc.identifier.urihttp://hdl.handle.net/11449/73420
dc.language.isoeng
dc.relation.ispartofBrazilian Journal of Veterinary Pathology
dc.relation.ispartofsjr0,162
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCD8 T cell
dc.subjectImmunohistochemistry
dc.subjectNelore breed
dc.subjectThymic lymphoma
dc.titleImmunophenotyping of thymic lymphoma in a Nelore cowen
dc.typeArtigo
dcterms.licensehttp://www.abpv.vet.br/paginas_site/default.asp?P=BJVP&PAG_SEQ=4282
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

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