Estudo das alterações eletrocorticográficas na insuficiência hepática aguda experimental.

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dc.contributor.authorSpadella, César Tadeu [UNESP]
dc.contributor.authorBacchi, C. E.
dc.contributor.authorHoshino, K.
dc.contributor.authorde Macedo, A. R.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T01:50:35Z
dc.date.available2014-05-27T01:50:35Z
dc.date.issued1986-10-01
dc.description.abstractThe aim of this study was to test the application and value of electrocorticography (ECG) in the early diagnosis and characterization of electrocorticograms changes on experimental fulminant hepatic failure (FHF). Our material was composed of two groups of guinea pigs: a) ethanolamine group--42 animals with FHF induced by intrabiliary injection of 2.5 ml of monoethanolamine oleate; b) control group--10 animals submitted to intrabiliary injection of 2.5 ml of saline. Electrocorticograms recordings were taken in both groups with the electrodes implanted on the parieto-occipital regions of the skull. The hepatic failure was characterized by clinical manifestations, serum biochemical tests and histopathological findings. In the early hepatic coma the electrocorticograms could not be unequivocally distinguished from normal pattern, and alpha rhythm was recognizable in most animals. With further deterioration of the clinical condition the tracing showed progressive slowness of the normal rhythm, increased voltage and triphasic waves followed by suppression of electrical activity preceding the animal death. The electrocorticography was not suitable for the early diagnosis of hepatic coma, since the ECG alterations became evident only in overt coma. However the method could be useful for the characterization of cerebral disorders and the study of the pathogenesis of fulminant hepatic failure.en
dc.format.extent229-235
dc.identifier.citationArquivos de Gastroenterologia, v. 23, n. 4, p. 229-235, 1986.
dc.identifier.issn0004-2803
dc.identifier.lattes6223012281302736
dc.identifier.scopus2-s2.0-0022788670
dc.identifier.urihttp://hdl.handle.net/11449/63772
dc.language.isopor
dc.relation.ispartofArquivos de Gastroenterologia
dc.relation.ispartofsjr0,396
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectethanolamine derivative
dc.subjectsodium chloride
dc.subjectanimal
dc.subjectbrain cortex
dc.subjectelectroencephalography
dc.subjectguinea pig
dc.subjecthepatic encephalopathy
dc.subjectiatrogenic disease
dc.subjectliver
dc.subjectmale
dc.subjectpathology
dc.subjectpathophysiology
dc.subjectAnimal
dc.subjectCerebral Cortex
dc.subjectElectroencephalography
dc.subjectEnglish Abstract
dc.subjectEthanolamines
dc.subjectGuinea Pigs
dc.subjectHepatic Encephalopathy
dc.subjectLiver
dc.subjectMale
dc.subjectSodium Chloride
dc.titleEstudo das alterações eletrocorticográficas na insuficiência hepática aguda experimental.pt
dc.title.alternativeElectrocorticographic changes in acute experimental hepatic insufficiencyen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/ag/paboutj.htm
unesp.author.lattes6223012281302736
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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