Value of Immunohistochemistry to Differentiate Digital Papillary Adenocarcinoma From Acral Hidradenoma With Papillary Structures
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Data
2022-11-01
Autores
Xavier-Júnior, José Cândido Caldeira [UNESP]
Camilo-Júnior, Deolino Joaõ
Carneiro Dias, André Luiz
Marques Ferreira, Pedro Paulo
Abdalla Filho, Antonio Roberto
Brenn, Thomas
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Resumo
Digital papillary adenocarcinoma is a malignant adnexal tumor with a predilection for acral sites. Hidradenoma is a benign solid and cystic sweat gland neoplasm with focal ductal and glandular differentiation and good outcomes. Hidradenomas can occur at acral sites and show papillary structures; for this reason, they are included in the differential diagnosis of digital papillary adenocarcinoma, and immunohistochemistry is a valuable tool in this scenario. We described a case of a 43-year-old man with an epithelial tumor showing papillary structures in the intermediate phalanx of the fourth finger. There was diffuse positivity for p63 and negativity for S100 protein, suggesting that this tumor was an acral hidradenoma with papillary structures.
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acral hidradenoma, adnexal tumors, dermatopathology, digital papillary adenocarcinoma, immunohistochemistry
Como citar
American Journal of Dermatopathology, v. 44, n. 11, p. 843-845, 2022.