Paracoccidioidomycosis in the region of Botucatu (state of São Paulo, Brazil). Evaluation of serum thyroxine (T4) and triiodothyronine (T3) levels and of the response to thyrotropin releasing hormone (TRH)

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dc.contributor.authorKiy, Yoshio [UNESP]
dc.contributor.authorMachado, Jussara Marcondes [UNESP]
dc.contributor.authorMendes, Rinaldo Poncio [UNESP]
dc.contributor.authorBarraviera, Benedito [UNESP]
dc.contributor.authorPereira, Paulo Camara Marques [UNESP]
dc.contributor.authorCury, Paulo Roberto [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T04:29:53Z
dc.date.available2014-05-27T04:29:53Z
dc.date.issued1988-07-01
dc.description.abstractT4, T3 and TSH serum levels were measured in 25 patients with paracoccidioidomycosis. Thyroid T3 reserves were measured on the basis of the increase in T3 (ΔT3) 2 h after intravenous injection of 200 μg TRH, and pituitary TSH reserves were measured on the basis of TSH increase (ΔTSH) 20 min after the same injection. Twenty healthy volunteers with no history of thyroid disease were used as controls. When the two groups were compared, the following results were obtained: (a) there was no significant difference in mean T4, T3, ΔTSH between groups; (b) reduced T3 levels were detected more frequently in patients with paracoccidioidomycosis, especially among those with the acute form of the disease or with the severely disseminated chronic form. The results suggest the occurrence of a reduction in peripheral conversion of T4 to T3, but do not indicate the occurrence of hypothyroidism in any of its forms (thyroid, pituitary or hypothalamic). © 1988 Kluwer Academic Publishers.en
dc.description.affiliationLaboratory of Nuclear Medicine School of Medicine - UNESP, Botucatu, 18.610, São Paulo
dc.description.affiliationDepartment of Infectious and parasitologic Diseases School of Medicine - UNESP, Botucatu, 18.610, São Paulo
dc.description.affiliationSection of Statistics School of Medicine - UNESP, Botucatu, 18.610, São Paulo
dc.description.affiliationUnespLaboratory of Nuclear Medicine School of Medicine - UNESP, Botucatu, 18.610, São Paulo
dc.description.affiliationUnespDepartment of Infectious and parasitologic Diseases School of Medicine - UNESP, Botucatu, 18.610, São Paulo
dc.description.affiliationUnespSection of Statistics School of Medicine - UNESP, Botucatu, 18.610, São Paulo
dc.format.extent3-9
dc.identifierhttp://dx.doi.org/10.1007/BF00437215
dc.identifier.citationMycopathologia, v. 103, n. 1, p. 3-9, 1988.
dc.identifier.doi10.1007/BF00437215
dc.identifier.issn0301-486X
dc.identifier.issn1573-0832
dc.identifier.lattes1365320427418204
dc.identifier.orcid0000-0001-5771-8943
dc.identifier.scopus2-s2.0-0023765920
dc.identifier.urihttp://hdl.handle.net/11449/63852
dc.language.isoeng
dc.relation.ispartofMycopathologia
dc.relation.ispartofjcr1.476
dc.relation.ispartofsjr0,597
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectparacoccidioidomycosis
dc.subjectT3
dc.subjectT4
dc.subjectthyroid
dc.subjectTRH
dc.subjectTSH
dc.subjectliothyronine
dc.subjectprotirelin
dc.subjectthyroxine
dc.subjectfungus
dc.subjectnonhuman
dc.subjectsouth american blastomycosis
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectHuman
dc.subjectMale
dc.subjectMiddle Age
dc.subjectParacoccidioidomycosis
dc.subjectProtirelin
dc.subjectThyroid Gland
dc.subjectThyrotropin
dc.subjectThyroxine
dc.subjectTriiodothyronine
dc.titleParacoccidioidomycosis in the region of Botucatu (state of São Paulo, Brazil). Evaluation of serum thyroxine (T4) and triiodothyronine (T3) levels and of the response to thyrotropin releasing hormone (TRH)en
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights
unesp.author.lattes1365320427418204[5]
unesp.author.lattes6840524602748457[4]
unesp.author.orcid0000-0001-5771-8943[5]
unesp.author.orcid0000-0002-9855-5594[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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